萘啶衍生物的合成研究进展  

Progress in Synthesis of Naphthidine Derivatives

作　　者：于雪[1] 柯苗 张娟[1] Yu Xue;Ke Miao;Zhang Juan(School of Pharmaceutical&Chemical Engineering,Xianyang Vocational Technical College,Xianyang Shaanxi 712000)

机构地区：[1]咸阳职业技术学院医药化工学院,陕西咸阳712000

出　　处：《山西化工》2022年第5期18-20,共3页Shanxi Chemical Industry

基　　金：咸阳职业技术学院2019年度科学研究项目(No.2019KYC06)。

摘　　要：萘啶化合物是一类分子结构特殊的含氮杂环有机化合物,在有机合成及药物合成等领域具有重要的用途。目前已经有许多构筑萘啶环衍生物的方法被报道,如Friedlaender反应法合成、Combes反应法合成、Gould-Jacobs反应法合成等。综述了萘啶衍生物的合成方法,期望为萘啶衍生物的合成方法开发提供新的思路,同时为合成结构新颖的萘啶药生物提供一定的借鉴和参考。Naphthidine compounds are a class of nitrogen-containing heterocyclic organic compounds with special molecular structures,which have important applications in organic synthesis and pharmaceutical synthesis.At present,there are many methods to construct the derivatives of naphthidine ring,such as Friedlaender reaction,Combes reaction,Gould-Jacobs reaction and so on.In this paper,the synthetic methods of naphthalene derivatives are reviewed.It is expected to provide a new idea for the development of the synthetic methods of naphthalene derivatives and a reference for the synthesis of novel structures of naphthalene derivatives.

关 键 词：萘啶衍生物 合成方法 研究进展 

分 类 号：O626.3[理学—有机化学]