Comparison of post-urethroplasty complication rates in pediatric cases with hypospadias using Vicryl or polydioxanone sutures  

作　　者：Mehdi Shirazi Abdolreza Haghpanah Anahita Dehghani Sezaneh Haghpanah Mehdi Ghahartars Mahdi Rahmanian 

机构地区：[1]Shiraz Nephro-urology Research Center,Shiraz University of Medical Sciences,Shiraz,Iran [2]Hematology Research Center,Shiraz University of Medical Sciences,Shiraz,Iran [3]Molecular Dermatology Research Center,Shiraz University of Medical Sciences,Shiraz,Iran [4]Medical School,MPH Department,Shiraz University of Medical Sciences,Shiraz,Iran

出　　处：《Asian Journal of Urology》2022年第2期165-169,共5页亚洲泌尿外科杂志（英文）

基　　金：The authors would like to thank Shiraz University of Medical Sciences,Shiraz,Iran and also Center for Development of Clinical Research of Nemazee Hospital and Dr.Nasrin Shokrpour for editorial assistance.

摘　　要：Objective:Hypospadias is a common congenital problem among male newborns.Both rapid absorbable sutures(polyglactin,Vicryl)and delayed absorbable sutures(polydioxanone,PDO)are used in hypospadias repair based on the surgeon's preference.This study was conducted to compare post-urethroplasty complication rates in pediatric patients with hypospadias using Vicryl or PDO sutures.Methods:This is a retrospective study which was designed and performed on 583 children aged 1-7 years old who had undergone hypospadias repair from January 2012 to December 2018.Required data were obtained from the patients'medical records.Results:Overall,post-surgical complications were observed in 60(10.3%)patients comprising urethro-cutaneous fistula(n=39,6.7%),meatal stenosis(n=10,1.7%),urethral stricture(n=7,1.2%),and glans dehiscence(n=4,0.7%).The mean age of the children with complications was 3.0±1.3 years.According to Kaplan-Meier estimate,the interval between surgery and development of complications was significantly shorter in the Vicryl group(p=0.037).Overall,complications were more prevalent in Vicryl suture than PDO suture(15.1%vs.5.3%,p<0.001).Regression model revealed that in comparison to the distal type,proximal hypospadias(odds ratio[OR]:103.9,95%confidence interval[CI]:32.2-334.9,p<0.001)and mid-shaft hypospadias(OR:82.9,95%CI:25.9-264.6,p<0.001)while using Vicryl suture instead of PDO suture(OR:62.4,95%CI:21.2-183.8,p<0.001)increased the odds of developing post-urethroplasty complications.Conclusion:We suggest PDO suture in the repair of hypospadias due to its lower complication rate,especially in cases of proximal and mid-shaft hypospadias which can get more complicated than the distal type.

关 键 词：HYPOSPADIAS Urinary fistula Polyglactin POLYDIOXANONE 

分 类 号：R695[医药卫生—泌尿科学]