心房颤动高功率短时程量化消融的研究进展  

Advances in high-power short-duration quantitative radiofrequency ablation of atrial fibrillation

作　　者：张宏亮 柳君楠 李栋 吴强[1,2] 白锋[1,2] ZHANG Hongliang;LIU Junnan;LI Dong;WU Qiang;BAI Feng(The Second Clinical Medical College of Lanzhou University,Lanzhou,730030,China;Department of Cardiology,the Second Hospital of Lanzhou University)

机构地区：[1]兰州大学第二临床医学院,兰州730030 [2]兰州大学第二医院心内科

出　　处：《临床心血管病杂志》2022年第7期531-535,共5页Journal of Clinical Cardiology

基　　金：甘肃省卫生行业科研计划项目(No:GSWSKY2018-19);甘肃省自然科学基金(No:20JR5RA343)。

摘　　要：肺静脉隔离是心房颤动消融治疗的基石。既往消融方式复杂耗时且远期复发率较高。消融指数和损伤指数为综合了消融功率、时间和压力的量化参数,其指导下的高功率短时程射频消融能显著缩短手术、消融时长,损伤效果更为持久。本综述旨在简述心房颤动射频消融治疗现况及主要挑战,并评估量化参数指导下高功率短时程消融策略的临床疗效和安全性。Pulmonary vein isolation is the cornerstone of atrial fibrillation ablation therapy.However,conventional ablation therapy is complicated and time-consuming,with disappointing long-term recurrence clinical outcomes.There are two surrogate endpoints in which contain complex mathematical formulas.Ablation index and lesion size index are the quantitative parameters corporating ablation power,contact force,and duration of ablation delivery.Both can effectively guide the clinician to achieve transmural lesions with high-power short-duration radiofrequency ablation,significantly shortening the duration of surgery and ablation.The purpose of this review is to summarize the current status and main challenges of radiofrequency ablation for atrial fibrillation and to evaluate the clinical efficacy and safety of the high-power short-duration ablation strategy under the guidance of quantitative parameters.

关 键 词：心房颤动 高功率短时程 肺静脉隔离 量化消融 

分 类 号：R541.7[医药卫生—心血管疾病]