预镇痛对多发伤患者疼痛和炎症的影响分析  

Influence Analysis of Preemptive Analgesia on Pain and Inflammation in Patients with Multiple Injuries

作　　者：郭俊杰 李自强 Guo Jun-jie;Li Zi-qiang(Department of Critical Care Medicine,Qingyang People's Hospital,Qingyang 745000,Gansu Province,China)

机构地区：[1]庆阳市人民医院重症医学科,甘肃庆阳745000

出　　处：《中国社区医师》2022年第24期6-8,共3页Chinese Community Doctors

摘　　要：目的:探讨预镇痛对多发伤患者疼痛和炎症的影响。方法:选取2020年4月-2021年4月庆阳市人民医院收治的96例多发伤患者作为研究对象,应用奇偶分组法分为两组,各48例。对照组行常规镇痛治疗,研究组行预阵痛治疗,比较两组视觉模拟评分(VAS)、全身性炎症反应综合征(SIRS)评分及治疗效果。结果:入组前,两组VAS评分比较,差异无统计学意义(P>0.05);入院后24 h、48 h、72 h、120 h、240 h,研究组VAS评分均低于对照组,差异有统计学意义(P<0.05)。入组前,两组SIRS评分比较,差异无统计学意义(P>0.05);入院后24 h、48 h、72 h、120 h、240 h,研究组SIRS评分均低于对照组,差异有统计学意义(P<0.05)。研究组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。结论:预镇痛对于多发伤患者具有积极意义,临床价值较高,不仅可以缓解疼痛及全身炎症反应综合征,还可促进患者康复,可作为首选干预方案。Objective: To explore the influence of preemptive analgesia on the pain and inflammation of patients with multiple injuries. Methods: A total of 96 patients with multiple injuries who were admitted to Qingyang People's Hospital from April 2020 to April 2021 were selected as the study subjects. The patients were divided into two groups according to the odd-even grouping method, with 48 cases in each group. The control group was given routine analgesia therapy and the study group was given preemptive analgesia therapy. The visual analogue scale (VAS), systemic inflammatory response syndrome (SIRS) score and treatment effect were compared between the two groups. Results: Before the enrollment, there was no significant difference in VAS scores between the two groups (P>0.05);At 24 h, 48 h, 72 h, 120 h, and 240 h after admission, the VAS scores of the study group were lower than those of the control group, and the difference was statistically significant (P<0.05). Before the enrollment, there was no significant difference in SIRS scores between the two groups (P>0.05). At 24 h, 48 h, 72 h, 120 h, and 240 h after admission, the SIRS scores of the study group were lower than those of the control group, and the difference was statistically significant (P<0.05). The total effective rate of treatment in the study group was higher than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: The preemptive analgesia has active significance and high clinical value in patients with severe multiple injuries, it can relieve pain and systemic inflammatory response syndrome, and also promote the recovery, serving as the preferred intervention regimen.

关 键 词：多发伤 预镇痛 疼痛 炎症 

分 类 号：R641[医药卫生—外科学]