双水平气道正压通气在早产儿呼吸窘迫综合征的应用及对早期肺功能的影响  

Application of Bilevel Positive Airway Pressure in Premature Infants with Respiratory Distress Syndrome and Its Effect on Early Pulmonary Function

作　　者：高燕 GAO Yan(Department of Neonatology,Caoxian People's Hospital,Heze,Shandong Province,274400 China)

机构地区：[1]曹县人民医院新生儿科,山东菏泽274400

出　　处：《系统医学》2022年第13期150-153,180,共5页Systems Medicine

摘　　要：目的探究早产儿呼吸窘迫综合征患儿接受双水平气道正压通气(bi-level positive airway pressure ventilation,BIPAP)治疗的应用效果及其对早期肺功能的影响。方法从2019年12月—2021年11月曹县人民医院新生儿科收治的早产儿呼吸窘迫综合征患儿中抽选76例作为观察对象,经数字表法分组,38例实施经鼻持续气道正压通气治疗患儿入选对照组,38例实施双水平气道正压通气治疗患儿入选观察组。评估患儿血气水平差异,统计患儿治疗后并发症情况。结果治疗1、24、72 h后,观察组患儿PaCO_(2)(43.36±1.22)mmHg、(42.09±1.33)mmHg、(37.08±2.72)mmHg,显著低于对照组,差异有统计学意义(P<0.05);观察组患儿PaO(62.61±3.29)mmHg、(72.26±2.71)mmHg、(91.88±5.29)mmHg,显著高于对照组,差异有统计学意义(P<0.05);观察组治疗后并发症发生率为26.32%,和对照组相比,差异无统计学意义(χ^(2)=0.066,P>0.05)。结论早产儿呼吸窘迫综合征患儿接受双水平气道正压通气治疗,对患儿血气水平具有调节作用,并发症少,对患儿早期肺功能影响小。Objective To investigate the application effect of bilevel positive airway pressure(BIPAP)in premature infants with respiratory distress syndrome and its effect on early pulmonary function.Methods From December 2019 to November 2021 in the department of neonatology of Caoxian People’s Hospital,76 cases of premature infants with respiratory distress syndrome were selected as observation objects.Grouped by the digital table method,38 children who were treated with nasal continuous positive airway pressure were selected as the control group.38 cases of children treated with bilevel positive airway pressure were selected into the observation group.The differences in blood gas levels of the children were evaluated,and the complications after treatment were counted.Results After 1 h,24 h,and 72 h of treatment,the PaCO_(2)in the observation group was(43.36±1.22)mmHg,(42.09±1.33)mmHg,and(37.08±2.72)mmHg,which were significantly lower than those in the control group,and the difference was statistically significant(P<0.05).The PaOof children in the observation group was(62.61±3.29)mmHg,(72.26±2.71)mmHg,and(91.88±5.29)mmHg,which were significantly higher than those in the control group,and the difference was statistically significant(P<0.05).The incidence of complications after treatment in the observation group was 26.32%,and there was no statistically significant difference compared with the control group(χ^(2)=0.066,P>0.05).Conclusion Bi-level positive airway pressure ventilation in preterm infants with respiratory distress syndrome has a regulating effect on blood gas levels,with few complications,and has little impact on the early pulmonary function of children.

关 键 词：早产儿 双水平气道正压通气 呼吸窘迫综合征 早期肺功能 

分 类 号：R272.1[医药卫生—中医儿科学]