门诊质子泵抑制剂用药情况与不合理用药分析点评  

Analysis and evaluation on the medication situation of proton pump inhibitors and irrational medication in the outpatient department

作　　者：梁成海 谭本仁[1] 陈金花 郑锦坤[1] 韩岳 谭仁飞 LIANG Chenghai;TAN Benren;CHEN Jinhua;ZHENG Jinkun;HAN Yue;TAN Renfei(Department of Pharmacy,Yue Bei People’s Hospital,Guangdong,Shaoguan 512026,China)

机构地区：[1]广东省粤北人民医院药学部,广东韶关512026

出　　处：《中国医药科学》2022年第16期114-117,141,共5页China Medicine And Pharmacy

摘　　要：目的了解粤北人民医院(我院)门诊质子泵抑制剂(PPIs)用药情况,分析点评PPIs不合理用药原因,进一步规范PPIs临床合理应用。方法从我院2021年1—7月医院信息系统(HIS)和医睦药事管理软件共抽取1400张PPIs门诊处方,参照《质子泵抑制剂临床应用指导原则(2020版)》等资料,结合我院处方点评制度,采用回顾性查阅的方法,对PPIs使用种类、使用人数、使用率、使用总数及各科室使用情况等进行统计分析,对PPIs的不合理使用情况进行分类讨论。结果我院门诊使用最多的PPIs为雷贝拉唑钠肠溶片10 mg,占49.64%,使用总数1545盒,雷贝拉唑钠肠溶片(包括10 mg和20 mg)使用率为83.78%;使用PPIs最多的科室是消化内科门诊,其次是急诊内科;不合理处方数最多的科室是心血管内科门诊;1400张PPIs门诊处方中,合理处方1234张,合理率为88.14%;不合理处方166张,不合理率为11.86%;不合理处方最多的类型是超适应证用药。结论我院PPIs存在不合理用药现象,需加强学习培训和反馈干预,提高PPIs合理用药率。Objective To understand the medication situation of proton pump inhibitors(PPIs)in the Outpatient Department of Yue Bei People’s Hospital(our hospital),to analyze and evaluate reasons for the irrational medication of PPIs,and to further standardize the rational clinical application of PPIs.Methods A total of 1400 PPIs of outpatient prescriptions from January to July 2021 were extracted from the hospital information system(HIS)and the medical and pharmaceutical affairs management software.Referring to the"Guiding Principles of Clinical Application of PPIs(2020 Edition)"and other materials,combined with the prescription evaluation system of our hospital,the types,number of users,utilization rate,total utilization number and utilization situation of various departments of PPIs were statistically analyzed by retrospective review.The irrational medication of PPIs was classified and discussed.Results The PPIs most used in the outpatient department of our hospital were rabeprazole enteric-coated tablets of 10 mg type,accounting for 49.64%,with a total of 1545 boxes.The utilization rate of rabeprazole sodium enteric-coated tablets(including 10 mg type and 20 mg type)was 83.78%.The department using PPIs most was the outpatient department of gastroenterology,followed by the emergency department of internal medicine.The department with the largest number of irrational prescriptions was the outpatient department of cardiovascular medicine.Of the 1400 PPIs outpatient prescriptions,1234 were rational prescriptions,with a rational rate of 88.14%.There were 166 irrational prescriptions,with an irrational rate of 11.86%.The most irrational prescription was the medication type of over-adaptation drugs.Conclusion Irrational medication exists in PPIs in our hospital,so it is necessary to strengthen learning and training and feedback intervention to improve the rational medication rate of PPIs.

关 键 词：质子泵抑制剂 调查分析 处方点评 合理用药 门诊患者 

分 类 号：R95[医药卫生—药学]