How to select the quantitative magnetic resonance technique for subjects with fatty liver:A systematic review  

作　　者：You-Wei Li Yang Jiao Na Chen Qiang Gao Yu-Kun Chen Yuan-Fang Zhang Qi-Ping Wen Zong-Ming Zhang 

机构地区：[1]Department of Radiology,Beijing Rehabilitation Hospital,Capital Medical University,Beijing 100144,China [2]Department of Rehabilitation Psychology,Beijing Rehabilitation Hospital,Capital Medical University,Beijing 100144,China [3]Department of Otorhinolaryngology,Beijing Rehabilitation Hospital,Capital Medical University,Beijing 100144,China [4]Department of Gastroenterology and Hepatology,Beijing Rehabilitation Hospital,Capital Medical University,Beijing 100144,China [5]Department of General Surgery,Beijing Electric Power Hospital,State Grid Corporation of China,Capital Medical University,Beijing 100073,China

出　　处：《World Journal of Clinical Cases》2022年第25期8906-8921,共16页世界临床病例杂志

基　　金：Supported by Beijing Municipal Science and Technology Commission,No.Z171100000417056;Key Support Project of Guo Zhong Health Care of China General Technology Group,No.SGGK202201001。

摘　　要：BACKGROUND Early quantitative assessment of liver fat content is essential for patients with fatty liver disease.Mounting evidence has shown that magnetic resonance(MR)technique has high accuracy in the quantitative analysis of fatty liver,and is suitable for monitoring the therapeutic effect on fatty liver.However,many packaging methods and postprocessing functions have puzzled radiologists in clinical applications.Therefore,selecting a quantitative MR imaging technique for patients with fatty liver disease remains challenging.AIM To provide information for the proper selection of commonly used quantitative MR techniques to quantify fatty liver.METHODS We completed a systematic literature review of quantitative MR techniques for detecting fatty liver,following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocol.Studies were retrieved from PubMed,Embase,and Cochrane Library databases,and their quality was assessed using the Quality Assessment of Diagnostic Studies criteria.The Reference Citation Analysis database(https://www.referencecitationanalysis.com)was used to analyze citation of articles which were included in this review.RESULTS Forty studies were included for spectroscopy,two-point Dixon imaging,and multiple-point Dixon imaging comparing liver biopsy to other imaging methods.The advantages and disadvantages of each of the three techniques and their clinical diagnostic performances were analyzed.CONCLUSION The proton density fat fraction derived from multiple-point Dixon imaging is a noninvasive method for accurate quantitative measurement of hepatic fat content in the diagnosis and monitoring of fatty liver progression.

关 键 词：Fatty liver Hepatic fat content ~1H-magnetic resonance spectroscopy Multiple-point Dixon imaging Two-point Dixon imaging 

分 类 号：R445.2[医药卫生—影像医学与核医学] R575.5[医药卫生—诊断学]