Glucose substrate in the hydrogen breath test for gut microbiota determination:A recommended noninvasive test  

作　　者：Qi-Qi Xie Jia-Feng Wang Yang-Fen Zhang Dong-Hui Xu Bo Zhou Ting-Hui Li Zhi-Peng Li 

机构地区：[1]School of Medicine,Taizhou University,Taizhou 318000,Zhejiang Province,China [2]Town Hospital of Gaodu,Mengyin County,Linyi 276200,Shandong Province,China

出　　处：《World Journal of Clinical Cases》2022年第26期9536-9538,共3页世界临床病例杂志

摘　　要：Intestinal dysbiosis and small intestinal bacterial overgrowth(SIBO)are common in patients with liver cirrhosis.Existing studies have not explored the association between gut dysbiosis and SIBO.We propose some suggestions for the authors’experimental methods and concepts,and we hope these suggestions can be adopted.The hydrogen breath test is worthy of recommendation due to its high accuracy and convenient operation.We suggest changing the substrate of the hydrogen breath test from lactulose to glucose to improve the accuracy of each parameter.SIBO is a small subset of gut dysbiosis,and we propose clarifying the concept of both.SIBO may be caused by liver cirrhosis or one of the pathogeneses of gastrointestinal diseases.Therefore,interference from other gastrointestinal diseases should be excluded from this study.

关 键 词：GLUCOSE Hydrogen breath test LACTULOSE Liver cirrhosis Small intestinal bacterial overgrowth 

分 类 号：R446.5[医药卫生—诊断学]