Safety and effectiveness of electromyography-induced rehabilitation treatment after epidural electrical stimulation for spinal cord injury:study protocol for a prospective,randomized,controlled trial  

作　　者：Xiao-Pei Sun Jie-Jian Shi Yong Bao Jie Zhang Hui-Juan Pan Dian-You Li Yu Liang Qing Xie 

机构地区：[1]Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,China [2]Shanghai Ruijin Rehabilitation Hospital,Shanghai,China

出　　处：《Neural Regeneration Research》2023年第4期819-824,共6页中国神经再生研究（英文版）

基　　金：supported by a grant from Shanghai Municipal Health Commission(General Program),No.202140221(to YB);Shanghai Municipal Key Clinical Specialty,No.shslczdzk02701。

摘　　要：Epidural electrical stimulation is a new treatment method for spinal cord injury(SCI).Its efficacy and safety have previously been reported.Rehabilitation treatment after epidural electrical stimulation is important to ensure and improve the postoperative efficacy of epidural electrical stimulation in patients with SCI.Considering that electromyography(EMG)-induced rehabilitation treatment can accurately match the muscle contraction of patients with SCI,we designed a study protocol for a prospective,randomized controlled trial.In this trial,on the premise of adjusting the spinal cord electrical stimulator to obtain the maximum EMG signal of the target muscle,patients with SCI receiving epidural electrical stimulation will undergo EMG-induced rehabilitation treatment.Recovery of muscle strength of key muscles,quality of life,safety and therapeutic effects will be monitored.Twenty patients with SCI who are scheduled to undergo epidural electrical stimulation in Shanghai Ruijin Rehabilitation Hospital will be randomly divided into two groups with 10 patients per group.The control group will receive conventional rehabilitation treatment.The EMG-induced rehabilitation group will receive EMG-induced rehabilitation treatment of the target muscles of the upper and lower limbs based on conventional rehabilitation treatment.After rehabilitation treatment,follow up for all patients will occur at 2 weeks and 1,3 and 6 months.The primary outcome measure of this trial will be evaluation of target muscle recovery using the Manual Muscle Testing grading scale.Secondary outcome measures will include modified Barthel Index scores,integrated EMG values,the visual analogue scale,Spinal Cord Independence Measure scores,and modified Ashworth scale scores.The safety indicator will be the incidence of adverse events.This trial will collect data regarding the therapeutic effects of EMG-induced rehabilitation in patients with SCI receiving epidural electrical stimulation for 6 months after rehabilitation treatment.Findings from this trial

关 键 词：electromyography-induced rehabilitation epidural electrical stimulation muscle strength pain quality of life randomized controlled trial recovery spinal cord injury 

分 类 号：R651.2[医药卫生—外科学]