肺部高频超声评分对新生儿呼吸窘迫综合征预测及预后评估的价值  

Value of lung high-frequency ultrasound score in the prediction and prognosis evaluation of neonatal respiratory distress syndrome

作　　者：高敏 张楠楠[1] 荣辉 毛国顺[1] Min Gao;Nan-nan Zhang;Hui Rong;Guo-shun Mao(Department of Pediatrics,Fuyang People's Hospital,Fuyang,Anhui 236000,China)

机构地区：[1]阜阳市人民医院儿科,安徽阜阳236000

出　　处：《中国现代医学杂志》2022年第17期81-87,共7页China Journal of Modern Medicine

基　　金：安徽省自然科学基金(No:2019B00185)。

摘　　要：目的探讨肺部高频超声评分对新生儿呼吸窘迫综合征预测及预后评估的价值。方法选取2020年2月—2022年1月阜阳市人民医院收治的107例新生儿呼吸窘迫综合征患儿为研究对象(研究组),另选取该院同期收治的无肺部疾病的48例新生儿为对照组。两组新生儿均行肺部高频超声检查。收集研究组患儿的基本资料,观察患儿治疗后7 d的预后;比较研究组、对照组肺部高频超声评分,比较研究组不同病情患儿的肺部高频超声评分;采用多因素Logistic回归分析影响新生儿呼吸窘迫综合征预后的因素;绘制ROC曲线分析肺部高频超声评分对新生儿呼吸窘迫综合征预后的预测价值。结果研究组肺部高频超声评分高于对照组(P<0.05)。重度病情组肺部高频超声评分高于轻度、中度病情组(P<0.05),中度病情组肺部高频超声评分高于轻度病情组(P<0.05)。多因素Logistic回归分析显示,胎龄[OR=4.968(95%CI:2.044,12.074)]、Δ肺部高频超声评分(治疗前与治疗后3 d评分差值)[OR=4.468(95%CI:1.839,10.859)]、机械通气时间[OR=5.540(95%CI:2.280,13.464)]是新生儿呼吸窘迫综合征预后的影响因素(P<0.05)。ROC曲线分析结果显示,肺部高频超声评分预测新生儿呼吸窘迫综合征预后的敏感性为73.33%(95%CI:0.448,0.911),特异性为84.78%(95%CI:0.754,0.911),AUC为0.820(95%CI:0.725,0.915)。结论新生儿呼吸窘迫综合征患儿肺部高频超声评分异常升高,并且肺部高频超声评分与新生儿呼吸窘迫综合征患儿的病情、预后有关,肺部高频超声评分评估新生儿呼吸窘迫综合征预后的效能良好。Objective To explore the value of lung high-frequency ultrasound score in the prediction and prognosis evaluation of neonatal respiratory distress syndrome.Methods A total of 107 neonatal respiratory distress syndrome infants admitted to the hospital from February 2020 to January 2022 were selected as the research objects,and recorded as the research group;48 neonates without pulmonary disease admitted to the hospital during the same period were also selected as the control group,all of whom underwent pulmonary high frequency ultrasonography.The basic data of the children in the study group were collected,and the treatment efficacy was counted after the children were followed up for 7 days after admission.The lung high-frequency ultrasound scores of the study group and the control group were analyzed.The high-frequency ultrasound scores of the lungs of children with different conditions in the study group were recorded.Factors affecting the short-term treatment efficacy of children with neonatal respiratory distress syndrome were analyzed.The predictive value of high-frequency lung ultrasound scores for treatment efficacy in children with neonatal respiratory distress syndrome was analyzed.Results The lung highfrequency ultrasound score in the study group was higher than that in the control group(P<0.05).The lung highfrequency ultrasound score of the severe disease group was higher than that of the mild and moderate disease groups(P<0.05),and the lung high-frequency ultrasound score of the moderate disease group was higher than that of the mild disease group(P<0.05).Logistic multivariate regression analysis showed:gestational age[OR=4.968(95%CI:2.044,12.074)],Δlung high-frequency ultrasound score(the difference between the scores before and 3 days after treatment)[OR=4.468(95%CI:1.839,10.859)],duration of mechanical ventilation[OR=5.540(95%CI:2.280,13.464)]was influential factors in the curative effect of children with neonatal respiratory distress syndrome(P<0.05).The results of ROC curve analysis showed that t

关 键 词：新生儿呼吸窘迫综合征 肺部超声 预测 预后 

分 类 号：R725.6[医药卫生—儿科]