单原子材料在电化学生物传感中的研究进展  

Recent Progress of Single-atom Materials in Electrochemical Biosensing

作　　者：江博文 陈敬轩 成永华 桑微 寇宗魁[1] JIANG Bowen;CHEN Jingxuan;CHENG Yonghua;SANG Wei;KOU Zongkui(State Key Laboratory of Advanced Technology for Materials Synthesis and Processing,Wuhan University of Technology,Wuhan 430070,China)

机构地区：[1]武汉理工大学材料复合新技术国家重点实验室,武汉430070

出　　处：《高等学校化学学报》2022年第9期123-136,共14页Chemical Journal of Chinese Universities

基　　金：湖北省自然科学基金(批准号:20211j0188)资助。

摘　　要：电化学传感器具有响应速度快、专一性强及准确性高等特点,已成为生物传感快速检测的重要发展方向之一,但目前难以达到对单个生物分子的检测水平,这主要受限于作为核心部件的探针材料.单原子材料由于其简单明确的原子局域结构,且具有媲美于生物酶的统一活性位点,是一种极具潜力的探针材料,因此受到了广泛关注.本文综合评述了具有均一局域配位环境的单原子材料的合成,以及其在电化学生物传感中的应用,并对单原子材料在未来电化学生物传感中面临的挑战和机遇进行了展望.Electrochemical sensors have become one of the important development directions for the rapid detection of biosensing on the basis of their fast response,strong specificity and high accuracy,but it is currently difficult to achieve the detection level of single biomolecules,mainly originating from the key probe materials.Single-atom materials featuring their simple and well-defined atomic localized structures have received extensive attention in the field of electrochemical biosensing due to a unified active site rivaling biological enzymes.Herein,the synthesis of single-atom materials with a homogeneous local coordination environment and their applications in electrochemical biosensing are reviewed.Moreover,the challenges and opportunities of single-atom materials in electrochemical biosensing are furtherly outlooked.

关 键 词：单原子材料 局域配位结构 电化学生物传感 健康监测 

分 类 号：O646[理学—物理化学]