生当归水煎液对血虚小鼠体重、脏器指数及葡萄糖-6-磷酸脱氢酶含量的影响  

Effects of Raw AngelicaDecoction on Body Weight,Organ Index and Content of Glucose-6-Phosphate Dehydrogenase in Mice with Blood Deficiency

作　　者：孙万奎 胡冰 SUN Wan-kui;HU Bing(Liangzhou District Animal Husbandry and Veterinary Technology Promotion Center,Wunuei Gansu 733000,China)

机构地区：[1]凉州区畜牧兽医技术推广中心,甘肃武威733000

出　　处：《畜牧兽医杂志》2022年第5期14-16,共3页Journal of Animal Science and Veterinary Medicine

摘　　要：分析生当归水煎液对乙酰苯肼及环磷酰胺致血虚模型小鼠体重、脏器指数及葡萄糖-6-磷酸脱氢酶含量的影响,以探讨生当归水煎液的补血作用机制。将80只清洁级昆明小鼠随机分为4组,分别为正常对照组、模型组、阳性对照组、当归水煎液组,测定各组小鼠全血中葡萄糖-6-磷酸脱氢酶的含量,并测定体重、胸腺指数及脾指数。与正常组相比,模型组小鼠给药前后体重、胸腺指数、脾指数及葡萄糖-6-磷酸脱氢酶的含量均显著降低(P<0.05);与模型组相比,阳性对照组和生当归水煎液组各项指标均显著升高(P<0.05)。结论:生当归水煎液对血虚小鼠具有一定的补血作用,其补血机制可能与提高血红蛋白的含量有关;同时,它还可能增强机体免疫机能。In this experiment,the effects of raw angelica decoction on body weight,organ index and glucose-6-phosphate dehydrogenase content of blood deficiency model mice induced by acetophenhydrazine and cyclophosphamide were investigated,and the blood-replenishing effect of raw angelica decoction was also discussed.In this experiment,80 clean grade Kunming mice were randomly divided into 4 groups,namely normal control group,model group,positive control group,and Angelica decoction group.We measured the content of glucose-6-phosphate dehydrogenase in the whole blood of mice in each group,and measured body weight,thymus index and spleen index.Compared with the normal group,the body weight,thymus index,spleen index and glucose-6-phosphate dehydrogenase content of mice in the model group were significantly decreased before and after administration(P<0.05).All indexes in the decoction group of raw angelica were significantly increased(P<0.05).The results showed that the decoction of raw angelica had a certain blood-replenishing effect on blood-deficiency mice.Its blood-replenishing mechanism may be related to increasing the content of hemoglobin,and may also enhance the immune function of the body.

关 键 词：当归水煎液 血虚 胸腺指数 脾指数 葡萄糖-6-磷酸脱氢酶 

分 类 号：S859.2[农业科学—临床兽医学]