严重冠状动脉左主干病变并Graves病1例报道并文献复习  

Severe left main coronary artery lesion complicated with Graves’disease:a case report and literature review

作　　者：周帝伶 郑惠娟 朱章志[2] ZHOU Diling;ZHENG Huijuan;ZHU Zhangzhi(Guangzhou University of Traditional Chinese Medicine,Guangzhou,Guangdong 510405,China;The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,Guangzhou,Guangdong 510405,China)

机构地区：[1]广州中医药大学,广州510405 [2]广州中医药大学第一附属医院,广州510405

出　　处：《重庆医学》2022年第17期2915-2917,2921,共4页Chongqing medicine

基　　金：国家自然科学基金项目(81873190)。

摘　　要：目的由临床病例延伸,讨论Graves病与冠状动脉病变相关性,为临床医疗提供参考。方法于国内外文献库中搜索相关文献,并结合临床病例具体情况进一步分析、探讨、总结Graves病与冠状动脉病变相关性。结果查证相关文献发现,Graves病患者即使不合并其他心血管事件危险因素,也可能因为甲状腺激素分泌异常对血管内皮细胞功能、凝血过程的影响而导致冠状动脉病变,罹患极严重的心血管事件。结论Graves病与冠状动脉病变存在相关性。Objective To discuss the correlation between Graves’disease and coronary artery lesions by extending clinical cases,and to provide reference for clinical treatment.Methods The relevant literature in domestic and international literature databases were searched,and the correlation between Graves’disease and coronary artery lesions was further analyzed,discussed,and summarized based on the specific clinical cases.Results Review of relevant literature found that patients with Graves’disease may suffer from coronary artery disease and extremely serious cardiovascular events due to the effects of abnormal thyroid hormone secretion on vascular endothelial function and coagulation process,even without other risk factors for cardiovascular events.Conclusion There is a correlation between Graves’disease and coronary artery lesions.

关 键 词：冠状动脉左主干 毒性弥漫性甲状腺肿 甲状腺功能亢进 血管内皮细胞 凝血 病例报道 

分 类 号：R581.1[医药卫生—内分泌]