疣状表皮发育不良伴回状颅皮  

Epidermodysplasia verruciformis associated with cutis vertices gyrate:a case report

作　　者：周立奉 路荣 ZHOU Li-feng;LU Rong(Department of Dermatology,the 942nd Hospital of the PLA,Yinchuan 750004,China)

机构地区：[1]中国人民解放军第九四二医院皮肤科,宁夏银川750004 [2]中国人民解放军第九四二医院病理科,宁夏银川750004

出　　处：《临床皮肤科杂志》2022年第9期527-530,共4页Journal of Clinical Dermatology

摘　　要：报告1例疣状表皮发育不良伴回状颅皮。患者男,20岁。头面部、双上肢丘疹12年余,头顶脑回状头皮11年。皮损头皮及额部为花斑癣样、面部为扁平疣样、双上肢为寻常疣样,头顶部脑回状颅皮。前臂疣状皮损组织病理检查:角化过度,棘层肥厚,表皮见弥漫性空泡化细胞,胞质为蓝灰色,部分细胞核固缩,呈发育不良外观。诊断:疣状表皮发育不良;回状颅皮。A case of epidermodysplasia verruciformis associated with cutis vertices gyrata is reported. A 20-year-old male presented with papules on the head,face and both upper limbs for more than 12 years and cutis vertices gyrata on the scalp for 11 years. Physical examination showed pityriasis versicolor-like lesions on the scalp and forehead, flat ward-like papules on the face, verruca vulgaris-like lesions on both upper lmbs, and cutis vertices gyrata on the scalp. Histopathological examination revealed hyperkeratosis and thickening of the spinous layer. Within the upper epidermis, there are vacuolated cells with a prominent perinuclear halo, bluish gray cytoplasm. The nuclei of some of those cells were condensed and appeared to be dysplastic. The diagnosis of epidermodysplasia verruciformis associated with cutis vertices gyrata was made.

关 键 词：皱褶性厚皮病 疣状表皮发育不良 回状颅皮 

分 类 号：R758.5[医药卫生—皮肤病学与性病学]