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作 者:杨华 YANG Hua(Department of Obstetrics and Pathology,People's Hospital of Pingyi County,Pingyi,Shandong Province,273300 China)
机构地区:[1]山东省平邑县人民医院产科,山东平邑273300
出 处:《世界复合医学》2022年第7期128-130,134,共4页World Journal of Complex Medicine
摘 要:目的探讨继发性宫缩乏力及宫缩乏力性产后出血的中西医结合治疗效果。方法将2020年3月—2021年3月山东省平邑县人民医院产科收治的78例继发性宫缩乏力及宫缩乏力性产后出血患者随机分为两组,每组39例。对照组使用米索前列醇联合欣母沛治疗,观察组在此基础上使用自拟益气化瘀缩宫汤治疗,对比两组疗效、止血各指标、应激反应指标。结果观察组治疗总有效率为97.44%,明显高于对照组的76.92%,差异有统计学意义(χ^(2)=7.341,P<0.05);观察组止血时间(24.73±5.21)min、产后2 h出血量(267.94±40.31)mL、产后24 h出血量(348.64±50.72)mL、晚期再出血率(2.56%)、产褥期感染率(2.56%)均明显低于对照组,差异有统计学意义(P<0.05);观察组治疗后肾上腺素(101.43±16.82)ng/mL、去甲肾上腺素(146.17±19.10)ng/mL、肾素(2.80±0.49)pg/mL、血管紧张素Ⅱ(30.37±5.42)pg/mL水平明显低于对照组,差异有统计学意义(P<0.05)。结论继发性宫缩乏力及宫缩乏力性产后出血的中西医结合治疗效果显著,能提升止血疗效,缩短止血时间,减少出血量,降低应激指标水平,具有积极的临床意义。Objective To investigate the effect of integrated traditional Chinese and Western medicine on secondary uterine atony and postpar⁃tum hemorrhage caused by uterine atony.Methods 78 patients with secondary uterine atony and uterine atony postpartum hemorrhage treated in the obstetrics department of Pingyi County People's Hospital of Shandong Province from March 2020 to March 2021 were randomly divided into two groups,39 cases in each group.The control group was treated with misoprostol combined with Ximupei.On this basis,the observation group was treated with self-made Yiqi Huayu Suogong Decoction.The curative effect,hemostasis indexes and stress response indexes were compared between the two groups.Results The total effective rate of treatment in the observation group was 97.44%,which was significantly higher than that in the control group(76.92%),and the difference was statistically significant(χ^(2)=7.341,P<0.05).The hemostasis time of the observation group was(24.73±5.21)min,the postpartum hemorrhage volume(267.94±40.31)mL,the postpartum hemorrhage volume(348.64±50.72)mL,the late rebleeding rate of 2.56%,and the puerperium infection rate of 2.56%were significantly lower than those of the control group,the difference was statistically significant(P<0.05).After treatment,the levels of epinephrine(101.43±16.82)ng/mL,norepi⁃nephrine(146.17±19.10)ng/mL,renin(2.80±0.49)pg/mL,and angiotensin II(30.37±5.42)pg/mL in observation group after treatment was significantly lower than the control group,the difference was statistically significant(P<0.05).Conclusion The treatment effect of integrated traditional Chinese and Western medicine on secondary uterine atony and postpartum hemorrhage caused by uterine atony is significant,which can improve the hemostasis effect,shorten the hemostasis time,reduce the bleeding volume,and reduce the level of stress indicators,which has positive clinical significance.
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