颈动脉体瘤患者血压变异与围术期并发症的相关性分析  

Correlation analysis of blood pressure variability and perioperative complications in patients with carotid body tumor

作　　者：黄勋 冯骏[1] 禄韶英[1] 杨林[1] 刘建林[1] Huang Xun;Feng Jun;Lu Shaoying;Yang Lin;Liu Jianlin(Department of Vascular Surgery,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)

机构地区：[1]西安交通大学第一附属医院血管外科,西安710061

出　　处：《中华血管外科杂志》2022年第2期132-136,共5页Chinese Journal of Vascular Surgery

摘　　要：目的分析颈动脉体瘤(CBT)患者血压变异与CBT围术期并发症的相关性,为临床上CBT患者围术期血压管理提供依据。方法回顾性分析2002年1月至2020年1月西安交通大学第一附属医院接受CBT手术的37例患者的临床资料。根据CBT切除术后是否发生围术期并发症分成并发症组及无并发症组。采用t检验比较两组患者基线资料及术前动态血压、血压变异两组指标,采用Pearson相关系分析研究血压变异相关指标与CBT围术期并发症的相关性。结果CBT患者中有8例术后发生并发症(并发症组),且并发症组患者年龄较无并发症组大[(52.3±11.3)岁比(39.4±10.5)岁,P<0.01]。各项动态血压指标在两组中差异无统计学意义(均P>0.05)。无并发症组24 h收缩压变异(24 h SSD)及夜间收缩压变异(nSSD)较并发症组低,差异均具有统计学意义[(10.23±1.75)mmHg比(14.24±3.53)mmHg,t=4.52,P<0.01;(8.45±1.92)mmHg比(13.15±3.24)mmHg,t=5.24,P<0.01]。24 h SSD与术中失血量及手术时间呈正相关性(均P<0.01)。结论CBT患者血压变异可能与围术期并发症有一定关联,加强24 h SSD及nSSD这两个血压变异性指标的监控,可以为CBT术前血压管理提供参考依据。Objective To explore correlation between blood pressure variability and perioperative complications in patients with carotid body tumor(CBT)and provide the basis for the perioperative blood pressure management of those patients.Methods Clinical data of 37 patients with CBT who had undergone surgical resection in the First Affiliated Hospital of Xi'an Jiaotong University from January 2002 to January 2020 were retrospectively analyzed.According to whether perioperative complications occurred after CBT resection,the patients were then divided into complication group and non-complication group.Baseline data,preoperative ambulatory blood pressure and blood pressure variability of the two groups were compared to study the correlation between blood pressure variability parameters and perioperative complications of CBT.T-test and Pearson correlation coefficient were used for comparison between the two groups.Results Postoperative complications occurred in 8 patients with CBT,and the age of patients in complication group was significantly older than that in non-complication group[(52.3±11.3)years vs(39.4±10.5)years,P<0.01].No significant difference in ambulatory blood pressure was observed between the two groups(all P>0.05).Besides,24h systolic blood pressure variation[24 h SSD;(10.23±1.75)mmHg vs(14.24±3.53)mmHg,t=4.52,P<0.01]and nocturnal systolic blood pressure variation[nSSD;(8.45±1.92)mmHg vs(13.15±3.24)mmHg,t=5.24,P<0.01]in non-complication group were lower than those in complication group.The difference between the two groups was statistically significant.Besides,24h SSD was positively correlated with intraoperative blood loss and operation time(all P<0.01).Conclusion The blood pressure variability of patients with CBT may be correlated to perioperative complications.Strengthening monitoring on those two blood pressure variability parameters,24h SSD and nSSD can provide an important reference for the preoperative blood pressure management of CBT.

关 键 词：血压变异 颈动脉体瘤 颈动脉体瘤切除术 围术期并发症 

分 类 号：R651.12[医药卫生—外科学]