4-硝基-N-丁基邻苯二甲酰亚胺的制备  

Synthesis of 4-Amino-N-butylphthalimide

作　　者：丁兴成 章文刚 宋龙锋 高立江 陈海滨 何江伟 DING Xing-cheng;ZHANG Wen-gang;SONG Long-feng;GAO Li-jiang;CHEN Hai-bin;HE Jiang-wei(Zhejiang Runtu Co.,Ltd,Shaoxing 312369,Zhejiang China)

机构地区：[1]浙江闰土股份有限公司,浙江绍兴312369

出　　处：《染料与染色》2022年第4期45-47,共3页Dyestuffs and Coloration

基　　金：浙江省万人计划科技创新领军人才资助项目(2019R52058)。

摘　　要：本文介绍了一种4-氨基-N-丁基邻苯二甲酰亚胺的合成方法。以苯酐和正丁胺为原料,合成了N-丁基邻苯二甲酰亚胺,然后采用混酸硝化一锅法工艺合成4-硝基-N-丁基邻苯二甲酰亚胺。考察了物料配比、反应温度、反应时间等因素对反应的影响。在最优条件下,4-硝基-N-丁基邻苯二甲酰亚胺的含量达到97%以上,总收率达到90%以上。A new synthetic process of 4-amino-N-butylphthalimide was introduced in this paper.Using phthalic anhydride and n-butylamine as raw materials,N-butylphthalimide was synthesized,and then 4-nitro-N-butylphthalimide was synthesized by mixed acid nitration and one-pot process.The effects of material ratio,reaction temperature,reaction time and other factors on the reaction were investigated.Under the optimal conditions,the purity of 4-nitro-N-butylphthalimide was over 97%,and the total yield was over 90%.

关 键 词：苯酐 正丁胺 混酸 硝化 4-硝基-N-丁基邻苯二甲酰亚胺 

分 类 号：TQ612.4[化学工程—精细化工]