超声造影在肺来源的颈部转移淋巴结病变中的诊断价值  

The Diagnostic Value of Contrasted Enhanced Ultrasound in Cervical Lymph Metastases Lesions Rooted in Lung

作　　者：郑鹏远[1] 佟凌霞[1] 齐娜[1] ZHENG Peng-yuan;TONG Ling-xia;QI Na(Department of Ultrasound,Jilin Provincial Cancer Hospital,Jilin Changchun 130012)

机构地区：[1]吉林省肿瘤医院超声科,吉林长春130012

出　　处：《中国医疗器械信息》2022年第15期68-70,共3页China Medical Device Information

基　　金：吉林省科技厅项目(项目名称:利用弹性成像和超声造影技术提高浅表淋巴结超声在判定性质、病理类型的精准性研究,项目编号:20200403087SF)。

摘　　要：目的:探讨超声造影在精准诊断肺来源的颈部转移淋巴结病变中的临床价值。方法:回顾性选取分析120例肺癌伴颈部淋巴结肿大的患者,进行常规超声及超声造影检查。所有淋巴结均具有穿刺病理结果证实。结果:在120个颈部转移淋巴结中,来源于肺鳞癌的40例,来源于肺腺癌的40例,来源于肺小细胞肺癌的40例。在超声造影的增强形态、是否均匀增强这两方面三组不同病理类型肺癌的颈部转移淋巴结间无明显差异(均P<0.05),超声造影的灌注缺损方面在肺鳞癌与肺腺癌的颈部转移淋巴结间有统计学差异(P<0.01);在肺小细胞癌与肺腺癌的颈部转移淋巴结间有统计学差异(P<0.01);而颈部转移淋巴结在鳞癌和小细胞癌之间无统计学差异(P>0.05)。超声造影时间-强度曲线(Intensity-Time Curve,TIC)参数的峰值强度(Peak Strength,PI)在在三组不同病理类型肺癌的颈部转移淋巴结间有明显差异(均P<0.01),TIC参数的达峰时间(Time to Peak,TTP)在三组不同病理类型肺癌的颈部转移淋巴结间无明显差异(均P>0.05),TIC参数的上升时间(Rise Time,RT)在三组不同病理类型肺癌的颈部转移淋巴结间有明显差异(均P<0.01)。结论:三组病理分型的颈部肺转移淋巴结超声造影特点,为分析判断颈部转移性淋巴结病变的病理类型提供了可靠的诊断信息。Objective:To explore the clinical value of CEUS in the accurate diagnosis of lung derived cervical metastatic lymph node lesions.All lymph nodes were confirmed pathologically.Methods:120 patients with of lung cancer and cervical lymphadenopathy were retrospectively selected and analyzed for routine ultrasound and contrast-enhanced ultrasound.All lymph nodes were confirmed by biopsy.Results:Among the 120 cervical metastatic lymph nodes,40 were sourced from pulmonary squamous cancer,while 40 rooted from adenocarcinoma of the lung,and 40 from small cell lung cancer.There was no significant difference between the three groups in terms of enhanced morphology and homogeneous enhancement of contrast-enhanced ultrasound(all P<0.05),and there was significant difference in perfusion defect between squamous cell carcinoma and adenocarcinoma(P<0.01);There was significant difference between small cell lung cancer and lung adenocarcinoma in cervical metastatic lymph nodes(P<0.01);There was no significant difference between squamous cell carcinoma and small cell carcinoma(P>0.05).There was significant difference in PI(peak intensity)of TIC parameters among the three groups of cervical metastatic lymph nodes with different pathological types of lung cancer(all P<0.01),no significant difference in TTP(peak time)of TIC parameters among the three groups of cervical metastatic lymph nodes with different pathological types of lung cancer(all P>0.05),and significant difference in RT(rise time)of TIC parameters among the three groups of cervical metastatic lymph nodes with different pathological types of lung cancer(all P<0.01).Conclusion:The CEUS characteristics of cervical pulmonary metastatic lymph nodes of the three groups of pathological types provide reliable diagnostic information for analyzing and judging the pathological types of cervical metastatic lymph node lesions.

关 键 词：肺癌 淋巴结 超声造影 时间-强度曲线 

分 类 号：R445.1[医药卫生—影像医学与核医学]