无创呼吸机辅助通气治疗慢性阻塞性肺疾病合并呼吸衰竭的临床效果  

Clinical effect of non-invasive ventilator-assisted ventilation in the treatment of chronic obstructive pulmonary disease complicated with respiratory failure

作　　者：陈晓珊 CHEN Xiao-shan(Guangdong Yanling Hospital,Guangzhou 510000,China)

机构地区：[1]广东燕岭医院,510000

出　　处：《中国实用医药》2022年第18期67-69,共3页China Practical Medicine

摘　　要：目的 探讨慢性阻塞性肺疾病 (COPD) 合并呼吸衰竭采用无创呼吸机辅助通气治疗的临床价值。方法 94 例 COPD 合并呼吸衰竭患者为研究对象 , 随机分为观察组与对照组 , 每组 47 例。对照组采用常规治疗 , 观察组采用无创呼吸机辅助治疗。对比两组治疗效果、治疗前后肺功能指标[第1 秒用力呼气容积 (FEV1)、用力肺活量 (FVC)]及血气分析指标[动脉血二氧化碳分压 (PaCO)、动脉血氧分压 (PaO)、动脉血氧饱和度 (SaO)]、并发症发生情况。结果 观察组治疗总有效率 95.74% 高于对照组的 72.34%, 差异有统计学意义 (P<0.05)。治疗后 , 观察组 FEV1、FVC 水平分别为 (1.87±0.55)、(2.95±0.78)L, 均高于对照组的 (1.49±0.33)、(2.45±0.53)L, 差异均有统计学意义 (P<0.05)。治疗后 , 观察组 PaO、SaO水平分别为 (9.85±0.72)kPa、(92.36±5.67)%, 高于对照组的 (8.54±0.81)kPa、(80.12±8.34)%,PaCO水平 (6.56±1.02)kPa 低于对照组的 (9.55±1.45)kPa, 差异均有统计学意义 (P<0.05)。观察组并发症发生率 4.26% 低于对照组的 17.02%, 差异有统计学意义 (P<0.05)。结论 无创呼吸机辅助通气治疗COPD 合并呼吸衰竭患者 , 可以纠正血气分析指标 , 改善患者肺功能 , 从而提高治疗效果 , 具有推广运用价值。Objective To discuss the clinical value of non-invasive ventilator-assisted ventilation in the treatment of chronic obstructive pulmonary disease (COPD) complicated with respiratory failure. Methods A total of 94 patients with COPD and respiratory failure were selected as the research subjects, and they were randomly divided into observation group and control group, with 47 cases in each group. The control group received conventional treatment, and the observation group received non-invasive ventilator-assisted ventilation. Both groups were compared in terms of therapeutic effect, pulmonary function indexes [forced expiratory volume in the1st second (FEV1), forced vital capacity (FVC)] and blood gas analysis indexes [arterial partial pressure of carbon dioxide (PaCO), arterial partial pressure of oxygen (PaO), blood oxygen saturation (SaO)], complications.Results The total effective rate 95.74% of the observation group was higher than 72.34% of the control group,and the difference was statistically significant (P<0.05). After treatment, the levels of FEV1 and FVC in the observation group were (1.87±0.55) and (2.95±0.78) L, which were higher than (1.49±0.33) and (2.45±0.53) L in the control group, and the differences were statistically significant (P<0.05). After treatment, the levels of PaOand SaOin the observation group were (9.85±0.72) kPa and (92.36±5.67)%, which were higher than (8.54±0.81) kPa and (80.12±8.34)% in the control group;the PaCOlevel (6.56±1.02) kPa of the observation group was lower than (9.55±1.45) kPa of the control group;all the differences were statistically significant (P<0.05). The complication rate 4.26% in the observation group was lower than 17.02% in the control group, and the difference was statistically significant (P<0.05). Conclusion Non-invasive ventilator-assisted ventilation in the treatment of COPD patients with respiratory failure can correct blood gas analysis and improve the lung function of patients,thereby improving the therapeutic effect, and has the value of po

关 键 词：呼吸衰竭 慢性阻塞性肺疾病 无创呼吸机 

分 类 号：R563[医药卫生—呼吸系统]