脱细胞技术在气管组织工程构建中的应用展望  

Application and prospect of decellularization technology in tissue engineered trachea

作　　者：王尧 钱军(综述)[1] 孙云浩 季明明 朱敏 许建宁(审校) WANG Yao;QIAN Jun;SUN Yun-hao;JI Ming-ming;ZHU Ming;XU Jian-ning(Department of Cardiothoracic Surgery,Yangcheng First Hospital,Affiliated Hospital of Nanjing University Medical School,Yancheng 224005,Jiangsu,CHINA)

机构地区：[1]南京大学医学院附属盐城第一医院(盐城市第一人民医院)胸心外科,江苏盐城224005

出　　处：《海南医学》2022年第17期2263-2266,共4页Hainan Medical Journal

基　　金：江苏省卫生健康委医学科研项目(编号:Z2020008);江苏省科协青年科技人才托举工程(编号:2020);江苏省盐城市医学科技发展计划项目(编号:YK2019001)。

摘　　要：近年来,脱细胞技术在气管组织工程的研究与应用已经成为当前的热点,并取得了一些进展。但是如何更好地将脱细胞气管基质应用于临床仍需要深入的研究。本文将对气管组织工程中不同脱细胞技术的优缺点及在长段气管损伤中的应用进行综述,并对未来的研究进行展望。In recent years,scientists paid close attention to the studies and applications of decellularization technology,which have made some progress.But how to promote decellularized matrix for clinical application still needs deeper research.Here we summarized the advantages and disadvantages of different acellular techniques in tissue engineered trachea and their applications in long tracheal injury therapy and provided a guidance of further investigations.

关 键 词：脱细胞技术 气管组织工程 脱细胞气管基质 长段气管损伤 进展 

分 类 号：R562.1[医药卫生—呼吸系统]