肺康复训练法联合无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并呼吸衰竭的临床疗效  

Clinical efficacy of pulmonary rehabilitation training combined with non-invasive ventilator in the treatment of acute exacerbation of chronic obstructive pulmonary disease complicated with respiratory failure

作　　者：谢其华[1] XIE Qihua(Department of Respiratory and Critical Care Medicine,Second Hospital of Sanming City,Sanming,Fujian,366000,China)

机构地区：[1]三明市第二医院呼吸与危重症医学科,福建三明366000

出　　处：《当代医学》2022年第18期164-167,共4页Contemporary Medicine

摘　　要：目的 探究肺康复训练法联合无创呼吸机治疗慢性阻塞性肺疾病急性加重期(AECOPD)合并呼吸衰竭的临床疗效。方法 选取2018年9月至2020年10月本院收治的114例慢性阻塞性肺疾病急性加重期合并呼吸衰竭患者作为研究对象,按照简单随机法分为对照组和实验组,每组57例。对照组给予无创呼吸机治疗,实验组在对照组基础上联合肺康复训练法治疗,比较两组肺功能[第1秒用力呼气容积(FEV1)、肺活量(VC)及最大通气量(MVV)]、动脉血气指标[动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))]及心肺氧合能力[代谢当量(MET)、最大摄氧量(VO_(2MAX))、主观用力等级(RPE)]。结果 治疗后,两组FEV1、VC、MVV水平均高于治疗前,且实验组高于对照组,差异有统计学意义(P<0.05)。治疗后,两组MET、VO_(2MAX)、RFE均高于治疗前,且实验组高于对照组,差异有统计学意义(P<0.05)。治疗后,两组PaO_(2)水平均高于治疗前,PaCO_(2)水平低均于治疗前,且实验组PaO_(2)水平高于对照组,PaCO_(2)水平低于对照组,差异有统计学意义(P<0.05)。结论 肺康复训练法联合无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并呼吸衰竭效果显著,有助于提高患者肺功能、动脉血气指标、心肺氧合能力,值得临床推广应用。Objective To explore the clinical efficacy of pulmonary rehabilitation training combined with non-invasive ventilator in the treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD) complicated with respiratory failure.Methods 114 patients with acute exacerbation of chronic obstructive pulmonary disease combined with respiratory failure who were admitted to our hospital from September2018 to October 2020 were selected as the research subjects,and they were divided into the control group and the experimental group according to the simple random method,with 57 cases in each group.The control group was given non-invasive ventilator treatment,and the experimental group was given pulmonary rehabilitation training on the basis of the control group,the pulmonary function(forced expiratory volume in one second[FEV1],vital capacity [VC] and maximal voluntary ventilation [MVV]),arterial blood gas indexes(arterial partial pressure of oxygen [PaO_(2)],partial pressure of carbon dioxide in arterial blood [PaCO_(2)]) and cardiopulmonary oxygenation capacity [metabolic equivalent(MET),maximal oxygen consumption(VO_(2MAX)),rating of perceived exertion(RPE)] were compared between the two groups.Results After treatment,the levels of FEV1,VC,and MVV in the two groups were higher than those before treatment,and the experimental group was higher than the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of MET,VO_(2MAX),and RFE in the two groups were higher than those before treatment,and the experimental group was higher than the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of PaO_(2) in the two groups were higher than those before treatment,and the levels of PaCO_(2) were lower than those before treatment,the levels of PaO_(2) in the experimental group were higher than those in the control group,and the levels of PaCO_(2) were lower than those in the control group,and the differences were statistically signif

关 键 词：肺康复训练法 无创呼吸机 慢性阻塞性肺疾病 急性加重期 

分 类 号：R563.9[医药卫生—呼吸系统] R563.8[医药卫生—内科学]