真菌球型鼻窦炎的CT特征及与血清BMP-2、EGF的关系  

Fungal Ball Sinusitis:CT Characteristics and Relationship with Serum BMP-2 and EGF

作　　者：赵兴泉[1] 钟渠[1] 高丽君 顾珊珊 李佳 陈茜 ZHAO Xingquan;ZHONG Qu;GAO Lijun;GU Shanshan;LI Jia;CHEN Qian(Department of Otorhinolaryngology,Sichuan Mianyang 404 Hospital,Mianyang 621000,Sichuan,P.R.China;Department of Imaging,The Second Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,P.R.China)

机构地区：[1]四川绵阳四〇四医院耳鼻咽喉科,四川绵阳621000 [2]川北医学院附属第二医院影像科,四川南充637000

出　　处：《影像科学与光化学》2022年第5期1169-1173,共5页Imaging Science and Photochemistry

摘　　要：本研究探讨真菌球型鼻窦炎的CT影像特征,以及与血清骨形态发生蛋白-2(BMP-2)、表皮生长因子(EGF)表达水平的关系。选取106例真菌球型鼻窦炎患者作为观察组,同时选取100例健康体检者作为对照组,给予CT检查,并检查血清BMP-2、EGF表达水平。观察组鼻中隔偏曲,以及中重度偏曲、高位偏曲比例明显高于对照组(P<0.05),观察组中鼻甲气化、钩突偏曲、钩突肥大及Haller气房比例明显高于对照组(P<0.05)。观察组血清BMP-2和EGF明显高于对照组(P<0.05)。观察组有鼻中隔偏曲、中鼻甲气化患者血清BMP-2和EGF水平较高(P<0.05)。真菌球型鼻窦炎患者鼻中隔偏曲、中鼻甲气化等结构变异发生率增高,血清BMP-2、EGF水平与鼻中隔偏曲、中鼻甲气化有关。This study investigated the CT image characteristics of fungal glomus sinusitis and its relationship with the expression of serum bone morphogenetic protein-2(BMP-2) and epidermal growth factor(EGF). 106 patients with fungal glomus sinusitis were selected as the observation group, and 100 healthy people were selected as the control group. All patients underwent the CT examination, and examined the serum BMP-2 and EGF expression levels. The proportion of nasal septum deviation, moderate and severe deviation, high deviation in the observation group were higher than those in the control group(P<0.05), the proportions of turbinate gasification, uncinate process deviation, uncinate process hypertrophy and Haller’s air chamber in the observation group were higher than those in the control group(P<0.05). Serum BMP-2 and EGF in the observation group were significantly higher than those in the control group(P<0.05). The levels of serum BMP-2 and EGF in patients with nasal septum deviation and middle turbinate gasification in the observation group were higher(P<0.05). The incidence of structural variation such as deviation of nasal septum and gasification of middle turbinate increased in patients with fungal sinusitis, and the levels of serum BMP-2 and EGF were related to deviation of nasal septum and gasification of middle turbinate.

关 键 词：真菌球型鼻窦炎 鼻中隔偏曲 中鼻甲气化 骨形态发生蛋白-2 表皮生长因子 

分 类 号：R765.9[医药卫生—耳鼻咽喉科] R816.96[医药卫生—临床医学]