SAHS患者自主神经损伤、动脉顺应性的超声参数变化  

Ultrasound Parameter Changes of Autonomic Nerve Injury and Arterial Compliance in Patients with SAHS

作　　者：王刚 徐琦 顾力 熊晶 杨婕 夏建国[1] WANG Gang;XU Qi;GU Li;XIONG Jing;YANG Jie;XIA Jianguo(Department of Ultrasonic Diagnosis,Wuhan Fourth Hospital,Wuhan 430034,Hubei,P.R.China;Department of Electrophysiology,Wuhan Fourth Hospital,Wuhan 430034,Hubei,P.R.China;Department of Respiratory Medicine,Wuhan Fourth Hospital,Wuhan 430034,Hubei,P.R.China)

机构地区：[1]武汉市第四医院超声科,湖北武汉430034 [2]武汉市第四医院心电生理科,湖北武汉430034 [3]武汉市第四医院呼吸科,湖北武汉430034

出　　处：《影像科学与光化学》2022年第5期1190-1194,共5页Imaging Science and Photochemistry

摘　　要：本文探讨阻塞性睡眠呼吸暂停低通气综合征(SAHS)患者的自主神经损伤、动脉顺应性超声参数的变化及其临床意义。选取140例SAHS患者作为SAHS组、另外选取70例无SAHS相关症状的志愿者作为对照组;采用超声测量两组研究对象的心功能参数、大动脉结构及功能参数、颈动脉脉搏波传导速度(PWV1)、降主动脉脉搏波传导速度(PWV2),并采用心电记录仪检测动态心电图参数的变化。SAHS组患者的PWV1、PWV2测定值大于对照组且差异具有统计学意义(P<0.05);SAHS组患者的总功率、极低频率、心率减速力(DC)测定值低于对照组且差异具有统计学意义(P<0.05),SAHS组的心率加速力(AC)测定值大于对照组(P<0.05);SAHS患者睡眠呼吸暂停低通气指数(AHI)测定值与PWV1、PWV2、AC呈显著正相关(P<0.05),SAHS患者AHI测定值与DC呈显著负相关(P<0.05)。SAHS患者可能存在自主神经损伤、动脉顺应性降低,并且与患者的睡眠呼吸暂停病情严重程度具有密切的相关性。This article discussed the changes of autonomic nerve injury, arterial compliance ultrasound parameters and their clinical significance in patients with obstructive sleep apnea hypopnea syndrome(SAHS). 140 SAHS patients were selected as the SAHS group, and 70 volunteers without SAHS-related symptoms were selected as the control group. The cardiac function parameters, aortic structure and function parameters, carotid pulse wave propagation speed(PWV1), descending aortic pulse wave velocity(PWV2) of the two groups of subjects were measured by ultrasound, and the Holter parameters changes were detected by electrocardiograph. The measured values of carotid pulse wave velocity(PWV1) and descending aortic pulse wave velocity(PWV2) in the SAHS group were significantly higher than those in the control group(P<0.05). The measured value of total power, very low frequency, and deceleration force(DC) were lower than that of the control group and the difference was significantly(P<0.05). The measured value of the heart rate acceleration force(AC) of the SAHS group was higher than that of the control group (P<0.05).The measured value of sleep-related apnea-hypopnea index(AHI)for SAHS patients was significantly positively correlated with PWV1,PWV2,AC (P<0.05),and the AHI measurement value in SAHS patients was significantly negatively correlated with DC(P<0.05).Patients with SAHS may have autonomic nerve damage and reduced arterial compliance,which are closely related to the severity of sleep apnea.

关 键 词：阻塞性睡眠呼吸暂停低通气综合征 自主神经损伤 动脉顺应性 超声 

分 类 号：R766[医药卫生—耳鼻咽喉科]