手性催化与合成中的一些凝聚态化学问题  

Condensed Matter Chemistry in Asymmetric Catalysis and Synthesis

作　　者：蒋茹 刘晨旭 杨平 游书力[1] Ru Jiang;Chenxu Liu;Ping Yang;Shuli You(State Key Laboratory of Organometallic Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China)

机构地区：[1]中国科学院上海有机化学研究所金属有机化学国家重点实验室,上海200032

出　　处：《化学进展》2022年第7期1537-1547,共11页Progress in Chemistry

基　　金：国家自然科学基金项目(No.91856201)资助。

摘　　要：凝聚态化学作为一门研究化学反应中凝聚态物质的科学,最近引起了化学界的广泛关注。从手性化学角度出发,本文列举了近年来手性催化与合成中的一些凝聚态化学现象,分类介绍了不对称催化反应中不同类型的凝聚态物质,并通过列举实例分析讨论了凝聚态物质的具体组成、层次结构等因素对反应的催化活性、对映及区域选择性控制影响,以望能引起业界对凝聚态科学的关注,启发更多学者从凝聚态化学角度思考有机化学反应本质并解决相关问题,完善凝聚态科学体系。Condensed matter chemistry,as a science of studying condensed matter in chemical reactions,has attracted extensive attention recently.In this review,condensed matter chemistry related to asymmetric catalysis and synthesis are briefly summarized,and different condensed matter phenomena in asymmetric catalytic reactions were classified.Besides,relative works were discussed in detail to illustrate the effects of the multi-level structures and composition of condensed matter on the catalytic activity,enantio-and regioselective control.It is hoped that the system of condensed matter science would be well developed by attracting more attention and bringing more thoughts to the essence of reaction from the perspective of condensed matter chemistry.

关 键 词：凝聚态 手性催化 对映选择性 非线性效应 溶剂效应 相转移催化 对映体自歧化 

分 类 号：O621.251[理学—有机化学]