甘肃省8~10岁儿童甲状腺径线与容积特征分析  

Characteristics of thyroid diameter and volume of children aged 8-10 years in Gansu Province

作　　者：费秀兰 朱小南[1] 王燕玲[1] 窦瑜贵[1] Fei Xiulan;Zhu Xiaonan;Wang Yanling;Dou Yugui(Gansu Center for Disease Control and Prevention,Lanzhou 730000,China)

机构地区：[1]甘肃省疾病预防控制中心地方病预防控制所,兰州730000

出　　处：《中华地方病学杂志》2022年第7期566-569,共4页Chinese Journal of Endemiology

基　　金：甘肃省卫生行业科研计划项目(GSWSKY2021-008)。

摘　　要：目的:分析甘肃省8~10岁儿童甲状腺径线与容积特征,为规范儿童甲状腺容积B超检查和制定儿童甲状腺容积正常参考值提供基础依据。方法:甘肃省8~10岁儿童甲状腺B超检查与尿碘测定资料来自甘肃省疾病预防控制中心地方病预防控制所。以甲状腺B超测量数据为基础,非参数检验法分析甲状腺各径线与容积的特征及关系。结果:8、9、10岁儿童( n = 500、503、496)尿碘中位数分别为166.62、167.16、178.78 μg/L。儿童甲状腺左右叶长、宽、厚以及容积均属偏态分布,左右叶间长、宽、厚以及容积各测量值均呈正相关( r = 0.76、0.85、0.72、0.88, P均< 0.001);甲状腺6条径线及容积值,性别间比较差异均无统计学意义( P均> 0.05),年龄间比较差异均有统计学意义( P均< 0.001);8、9、10岁儿童甲状腺容积均值分别为2.6、2.9、3.2 ml,中位数分别为2.5、2.7、3.0 ml,第97百分位数( P97)分别为4.4、4.9、6.5 ml,10岁组高于国家现行标准(6.0 ml);县级8、9、10岁儿童甲状腺容积中位数范围分别为1.8~4.1、1.8~4.3、1.9~4.4 ml,各年龄组县级儿童甲状腺容积比较差异均有统计学意义( P均< 0.05)。 结论:甘肃省8~10岁儿童甲状腺容积 P97值较国家标准相比略有变化;甲状腺容积参考值应依年龄制定,同一年龄不同性别可使用统一参考值。Objective To analyze the characteristics of thyroid diameter and volume of children aged 8-10 years in Gansu Province,and to provide a basis for standardizing B-ultrasound examination of children's thyroid volume and establishing a normal reference value of children's thyroid volume.Methods The data of thyroid volume by B-ultrasound and urinary iodine determination of children aged 8-10 years in Gansu Province were from Institute of Endemic Disease,Gansu Center for Disease Control and Prevention.Based on the measured data of thyroid B-ultrasound of 8-10 years children in Gansu Province,the characteristics and relationship between thyroid diameter and volume were analyzed by nonparametric test.Results The medians of urinary iodine of 8,9,10 years children(n=500,503,496)were 166.62,167.16 and 178.78μg/L,respectively.The length,width,thickness and volume of the left and right lobes of the thyroid in children were skewed distribution.There was a positive correlation between the left and right diameters(length,width and thickness)and between left and right thyroid volumes(r=0.76,0.85,0.72,0.88,P<0.001).There was no significant difference in the six diameter lines and volume values of thyroid between genders(P>0.05),but there was significant difference between ages(P<0.001).The means thyroid volume of 8,9 and 10 years children were 2.6,2.9 and 3.2 ml,respectively,the medians were 2.5,2.7 and 3.0 ml,respectively,and the 97th percentile(P97)were 4.4,4.9 and 6.5 ml,respectively.The thyroid volume of 10 years group was higher than the current national standard(6.0 ml).The median ranges of thyroid volume of children aged 8,9 and 10 years at the county level were from 1.8 ml to 4.1 ml,from 1.8 ml to 4.3 ml and from 1.9 ml to 4.4 ml,respectively.There was significant difference in thyroid volume of children at the county level in all age groups(P<0.05).Conclusions Compared with the national standard,the P97 value of thyroid volume of children aged 8-10 years in Gansu Province is slightly different.The reference value of thyr

关 键 词：儿童 甲状腺容积 B超 

分 类 号：R725.8[医药卫生—儿科]