基于脱氧核酶的生物传感器的实际应用  

Practical Aplications of DNAzyme-Based Bosensors

作　　者：古宗利 赵继宽[1] 刘树峰[1] Gu Zongli;Zhao Jikuan;Liu Shufeng(College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao266042,China)

机构地区：[1]青岛科技大学化学与分子工程学院,山东青岛266042

出　　处：《山东化工》2022年第16期170-173,176,共5页Shandong Chemical Industry

摘　　要：自近30年前发现脱氧核酶以来,脱氧核酶已广泛应用于生物传感领域。电化学法、荧光、比色法、电化学发光、化学发光、光电化学等检测方法在基于脱氧核酶的生物传感器中广泛应用于生物样品方面的检测。主要讨论了现有的基于脱氧核酶的生物传感器的几种常见检测方法在检测生物样品方面的实际应用,并且讨论了几种检测方法的优缺点,并指出了现有研究的不足之处。Since DNAzymes were discovered nearly 30 years ago,DNAzymes have been widely used in the field of biosensing.Electrochemical,fluorescence,colorimetric,electrochemiluminescence,chemiluminescence,photoelectrochemical and other detection methods are widely used in the detection of biological samples in DNAzyme-based biosensors.This paper mainly discusses the practical application of several common detection methods of existing DNAzyme-based biosensors in the detection of biological samples,and discusses the advantages and disadvantages of several detection methods,and points out the shortcomings of existing research.

关 键 词：脱氧核酶 生物传感器 生物样品检测 检测方法 

分 类 号：TQ591[化学工程—精细化工]