基于多层螺旋CT肾脏特征预测分侧肾功能的价值  

The value of predicting lateral renal function based on renal features of multi-slice spiral CT

作　　者：张智博 高知玲[2] 李修元 翟文鹏 吴静芝 孙长浩 陈勇[3] ZHANG Zhibo;GAO Zhiling;LI Xiuyuan;ZHAI Wenpeng;WU Jingzhi;SUN Changhao;CHEN Yong(Ningxia Medical University,Yinchuan 750004,China;Department of Radiology,General Hospital of Ningxia Medical University,Yinchuan 750004,China;Department of Interventional Radiology,General Hospital of Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏医科大学,宁夏银川750004 [2]宁夏医科大学总医院放射科,宁夏银川750004 [3]宁夏医科大学总医院放射介入科,宁夏银川750004

出　　处：《实用放射学杂志》2022年第7期1126-1129,1139,共5页Journal of Practical Radiology

基　　金：宁夏自治区重点研发项目(2018BFH03021)。

摘　　要：目的探讨基于CT扫描及后处理技术测量肾脏皮质厚度(RCT)、皮质容积(RCV)与分侧肾滤过功能的关系,并评价其预测分侧肾滤过功能的价值。方法选择行增强CT扫描患者93例,并于1周内对其行肾动态显像(RDI)检查。以测得的肾小球滤过率(GFR)为金标准,分为正常组、减退组、受损组。比较3组间RCT和RCV的差异,分析其与GFR的相关性,并用受试者工作特征(ROC)曲线评价两者预测分侧肾功能优劣的价值。结果3组RCT分别为(0.55±0.14)cm、(0.44±0.10)cm、(0.31±0.10)cm。RCV分别为(75.24±15.82)cm^(3)、(54.29±14.72)cm^(3)、(30.18±11.38)cm^(3)。3组间RCT、RCV差异有统计学意义(F=61.17与F=142.12,P<0.05),与单侧肾GFR高度正相关(r=0.868与r=0.920,P<0.05),RCT及RCV在预测肾功能异常患者时曲线下面积(AUC)分别为0.828、0.905。结论经CT及后处理技术测得RCT及RCV能较准确反映GFR,可以作为预测分侧肾功能优劣的有用指标。Objective To explore the relationship between renal cortical thickness(RCT)or renal cortical volume(RCV)and lateral renal filtration function based on CT scanning and post-processing techniques,and to evaluate the value of them in predicting lateral renal filtration function.Methods A total of 93 patients who underwent enhanced CT scan were selected and underwent renal dynamic imaging(RDI)within 1 week.Taking the glomerular filtration rate(GFR)measured by RDI as the gold standard,they were divided into normal group,decreased group,and damaged group.The differences of RCT and RCV among the three groups were compared,and the correlation between RCT,RCV and GFR was analyzed.Receiver operating characteristic(ROC)curve was used to evaluate the value of the two in predicting the pros and cons of lateral renal function.Results The three groups of RCT were(0.55±0.14)cm,(0.44±0.10)cm,and(0.31±0.10)cm.TheRCVwere(75.24±15.82)cm^(3),(54.29±14.72)cm^(3),and(30.18±11.38)cm^(3).There were statistically significant dfferences in RCT and RCV among the threegroups(F=61.17 and F=142.12,P<0.05).RCT,RCV and unilateral renal GFR were highly positively correlated(r=0.868 and r=0.920,P<0.05).The area under the curve(AUC)of RCT and RCV in predicting patients with abnormal renal function were 0.828 and 0.905 respectively.Conclusion RCT and RCV measured by CT and post-processing techniques can reflect GFR more accurately,and both can be used as useful indicators for predicting lateral renal function.

关 键 词：肾小球滤过率 肾皮质厚度 肾皮质容积 计算机体层成像 

分 类 号：R322.61[医药卫生—人体解剖和组织胚胎学] R814.42[医药卫生—基础医学]