基于数据挖掘中药治疗干眼的文献计量分析  

Bibliometric analysis of Traditional Chinese Medicine treatment for dry eye based on Data Mining

作　　者：孙静[1] 周利华[1] 倪娟 王维利[1] SUN Jing;ZHOU Lihua;NI Juan;WANG Weili(Anhui Medical University,Hefei 230032,China)

机构地区：[1]安徽医科大学,合肥230032 [2]湖南中医药大学,长沙410208

出　　处：《中国中医眼科杂志》2022年第9期703-707,共5页China Journal of Chinese Ophthalmology

基　　金：安徽省名师工作室(2014msgzs137);安徽医科大学青年科学基金(2021xkj259)。

摘　　要：目的通过对数据的整合,分析中药治疗干眼的研究趋势和用药特点,为进一步开展干眼的治疗研究提供参考。方法选取2010年1月1日—2020年12月31日中国知网、万方和维普数据库中关于中药治疗干眼的临床研究文献。由2位医师对纳入的文献进行全文阅读,提取文献的时间、期刊源分布、中药方剂、单味中药、中药方剂应用方式等关键信息。采用Endnote X 9.0去除重复文献,应用Excel 2017建立数据库并进行频数统计。结果(1)一般情况:本研究最终纳入文献368篇。共涉及中药方剂162个,给药方式9种;中药238味;被中国知网、万方、维普数据库收录并发表与中药治疗干眼相关文献的期刊共134种。(2)时间分布:发文量排在前5位的年份分别为2020年(59篇,16.03%)、2017年(49篇,13.32%)、2018年(45篇,12.23%)、2015年(39篇,10.60%)、2016年(37篇,10.05%)。(3)方剂应用频次:使用频次≥4次的方剂共20个,排在前5位的分别为杞菊地黄汤(29次,7.88%)、逍遥散(10次,2.72%)、除风益损汤(9次,2.45%)、清眩润目饮(9次,2.45%)、桑白皮汤(9次,2.45%)。(4)方剂给药方式频次:给药方式频次排在前5位的分别为:口服(269次,73.10%)、熏蒸法(56次,15.22%)、口服+熏蒸法(22次,5.98%)、离子导入法(12次,3.26%)、口服+热敷法(3次,0.82%)。(5)中药使用频次:使用频次≥50次的中药共19味,排在前5位的分别为:菊花(213次,57.88%)、枸杞子(195次,52.99%)、麦冬(190次,51.63%)、甘草(149次,40.49%)、生地黄(146次,39.67%)。(6)期刊源分布:期刊发文量排名前5位的是《中国中医眼科杂志》(23篇,6.25%)、《新中医》(17篇,4.62%)、《光明中医》(15篇,4.08%)、《实用中医药杂志》(12篇,3.26%)、《四川中医》(12篇,3.26%)。结论中药治疗干眼发表的文献数量整体呈波动上升趋势,中药治疗干眼有十分重要的参考价值。OBJECTIVE To analyze the research trend and medication characteristics of Traditional Chinese Medicine(TCM)in the treatment of dry eye through the integration of data,so as to provide references for further research on the treatment of dry eye.METHODS The clinical research literature on the treatment of dry eye with TCM in the databases of CNKI,Wanfang and VIP from January 1^(st),2010 to December 31^(st),2020 were retrieved.Two doctors read full text of the included literature to extract the key information such as the publication time,the distribution of journal sources,TCM prescriptions,single Chinese medicine,and the application mode of TCM prescriptions.Endnote X 9.0 was used to remove duplicate literature,and Excel 2017 was used to establish a database and perform frequency analysis.RESULTS(1)General information:A total of 368 articles were included in this study.Altogether 162 Chinese medical formulas TCM prescriptions,nine different modes of administration and 238 Chinese medicines were involved.A total of 134 journals in CNKI,Wanfang and VIP databases published literature related to the treatment of dry eye with TCM treatment.(2)Time distribution:The top five years in the number of published articles were 2020(59 articles,16.03%),2017(49 articles,13.32%),2018(45 articles,12.23%),2015(39 articles,10.60%)and 2016(37 articles,10.05%),respectively.(3)Frequency of TCM prescriptions:There were twenty TCM prescriptions that were used no less than 4 times.The top five with highest frequencies were Qiju Dihuang Decoction(29 times,7.88%),Xiaoyao San(ten times,2.72%),Chufeng Yisun Decoction(nine times,2.45%)and Qingxuan Runmu Decoction(nine times,2.45%),Sangbaipi Decoction(nine times,2.45%).(4)Frequency of application modes:The top five administration modes were oral(269 times,73.10%),fumigation(56 times,15.22%),oral+fumigation(22 times,5.98%),iontophoresis(12 times,3.26%)and oral+hot compress treatment(three times,0.82%).(5)Frequency of Chinese medicines:There were nineteen Chinese herbs that were used no less than

关 键 词：干眼 中药 用药规律 计量分析 

分 类 号：R276.7[医药卫生—中医五官科学]