框架诱导组装策略研究进展  

Recent Advancements in Frame-guided Assembly

作　　者：袁伟 董原辰 Wei Yuan;Yuan-chen Dong(CAS Key Laboratory of Colloid,Interface and Chemical Thermodynamics,Institute of Chemistry,Chinese Academy of Sciences,Beijing 100190;University of Chinese Academy of Sciences,Beijing 100049)

机构地区：[1]中国科学院化学研究所,中国科学院胶体、界面与化学热力学重点实验室,北京100190 [2]中国科学院大学,北京100049

出　　处：《高分子学报》2022年第10期1204-1216,共13页Acta Polymerica Sinica

基　　金：北京市自然科学基金(基金号Z180016);国家自然科学基金(基金号21971248);北京分子科学国家研究中心(基金号C220200701)资助项目.

摘　　要：近年来,两亲分子自组装在生物医药和材料科学领域受到愈加广泛的关注和研究.为了实现特定大小和形态的功能纳米结构的制备,研究者们先后发展了多种稳健的构筑方法.框架诱导组装策略作为一种新兴的有效构筑策略,在精确形貌和尺寸可控的三维纳米囊泡和二维纳米膜方面都取得了一系列重要的研究成果.本文总结并评了述了框架诱导组装策略近十年来的重要研究进展,并展望了该策略在未来存在的挑战和应用前景.Self-assembly of amphiphiles has attracted more and more attention in the fields of biomedicine and materials science during the last decade.For preparing functional nanostructures with specific size and morphology,researchers have developed a variety of robust construction methods,including film hydration,co solvent,dialysis,microfluidic technologies as well as well frame-guided assembly method,etc.Since the traditional methods have already been well-summarized in detail in many references,therefore,only the construction mechanism and features of these strategies will be addressed here.As a new and effective construction strategy,frame-induced assembly has achieved a series of important achievements in fabrication of three dimensional nanovesicles and two dimensional nanomembranes with precise control on their morphology and size.Based on this novel method,various scaffolds and leading hydrophobic groups have been proven adaptable to form customized nanostructures.In this review,the important research progress of frame-induced assembly strategy in recent ten years will be summarized and evaluated,and the challenges and application prospects of this strategy in the future will be also forecasted.

关 键 词：两亲分子 自组装 组装方法 框架诱导组装 

分 类 号：O641.3[理学—物理化学]