Prevalence and fuoroquinolone resistance of Campylobacter spp.isolated from beef cattle in Japan  

作　　者：Yoshimasa Sasaki Hiroshi Asakura Tetsuo Asai 

机构地区：[1]Division of Biomedical Food Research,National Institute of Health Sciences,3‑25‑26,Tonomachi,Kawasaki‑ku,Kawasaki,Kanagawa 210‑9501,Japan [2]The United Graduate School of Veterinary Science,Gifu University,1‑1,Yanagido,Gifu 501‑1193,Japan

出　　处：《Animal Diseases》2022年第3期181-186,共6页动物疾病（英文）

基　　金：supported by grants from the Ministry of Health,Labor,and Welfare of Japan(21KA1004).

摘　　要：Beef is a source of human Campylobacter infections.Antimicrobial treatment is needed when patients are immuno‑compromised or have other comorbidities.Therefore,we investigated the prevalence and antimicrobial resistance of Campylobacter spp.in beef cattle in Japan.Rectal swab samples were collected from 164 beef cattle at an abattoir between March 2021 and August 2021,and Campylobacter spp.were isolated from 94(57.3%)cattle.C.jejuni and C.coli were isolated from 68 and 26 cattle,respectively.For Campylobacter jejuni,the resistant rates against ampicillin,tetracycline and ciprofoxacin were 20.6,75.0 and 64.7%,respectively.For C.coli,the resistant rates against ampicil‑lin,tetracycline and ciprofoxacin were 53.8,76.9 and 88.5%,respectively.No Campylobacter isolates were resistant to erythromycin.By multilocus sequence typing,C.jejuni and C.coli isolates were classifed into 22 and 2 sequence types(STs).The top three STs of C.jejuni were ST806(12 isolates),ST21(nine isolates),and ST459(eight isolates).The most frequent ST of C.coli was ST1068(23 isolates).The results suggest that Campylobacter spp.are prevalent in the gastrointestinal tract of beef cattle slaughtered at abattoirs.Furthermore,the administration of erythromycin is efec‑tive against human campylobacteriosis caused by beef consumption.Monitoring the prevalence and antimicrobial resistance of Campylobacter spp.in beef cattle could be useful for managing the risk of human campylobacteriosis.

关 键 词：Antimicrobial resistance Beef cattle CAMPYLOBACTER Fluoroquinolone resistance Multilocus sequence typing 

分 类 号：S858.292[农业科学—临床兽医学]