血液透析-灌流串联治疗尿毒症血液透析顽固性高血压患者的效果  

Effect of Hemodialysis Perfusion in Series on Refractory Hypertension in Uremic Hemodialysis Patients

作　　者：于小函 李曼[1] YU Xiaohan;LI Man(Department of Nephrology,Shenyang Fourth People's Hospital,Shenyang 110000,China)

机构地区：[1]沈阳市第四人民医院肾内科,辽宁沈阳110000

出　　处：《中国医药指南》2022年第26期57-59,共3页Guide of China Medicine

摘　　要：目的评价尿毒症血液透析顽固性高血压患者行血液透析-灌流串联治疗的可行性和临床效果。方法选择我院2018年2月至2019年4月收治的尿毒症血液透析顽固性高血压患者84例,结合治疗方案的不同进行分组,对照组(n=42)患者采取常规血液透析治疗,观察组(n=42)患者采取血液透析-灌流串联治疗。比较两组患者的治疗效果、收缩压(SBP)、舒张压(DBP)以及生活质量,以生活质量综合评定问卷-74(成人用)(GQOL-74)评估患者的生活质量。结果在血压水平方面,治疗前两组患者的SBP、DBP水平比较接近,P>0.05,治疗后比较治疗前两组SBP、DBP水平均改善,且观察组SBP[(138.20±9.30)mm Hg vs.(165.80±12.30)mm Hg]、DBP[(84.20±6.05)mm Hg vs.(98.80±7.60)mm Hg]水平均低于对照组,P<0.05;观察组患者治疗总有效率为97.61%,明显高于对照组的80.95%,P<0.05;在生活质量方面,观察组患者躯体功能评分[(88.80±5.50)分vs.(80.50±3.50)分]、心理功能评分[(92.05±4.50)分vs.(82.50±4.30)分]、社会功能评分[(90.20±4.50)分vs.(80.80±4.30)分、物质生活评分[(89.80±6.50)分vs.(80.50±4.50)分]均明显高于对照组,P<0.05。结论对比单纯血液透析治疗,血液透析-灌流串联治疗尿毒症血液透析顽固性高血压降压效果显著,有助于改善患者的预后,提升其生活质量。Objective To evaluate the feasibility and clinical effect of hemodialysis-perfusion tandem treatment in patients with uremic hemodialysis and refractory hypertension.Methods Select 84 patients with uremic hemodialysis and refractory hypertension admitted to our hospital from February 2018 to April 2019,combined with the treatment plan for randomization,patients in the control group(n=42)were treated with conventional hemodialysis,and patients in the observation group(n=42)were treated with hemodialysis-perfusion series treatment.The treatment effect,systolic blood pressure(SBP),diastolic blood pressure(DBP)blood pressure level and quality of life were compared,the quality of life comprehensive assessment generic quality of life inventory-74(for adults,GQOL-74)to assess the quality of life of patients.Results In terms of blood pressure level,before treatment,the SBP and DBP levels of uremic hemodialysis-resistant hypertension patients in the two groups were relatively close,P>0.05,and after treatment,the SBP and DBP levels before treatment were improved,and the observation group SBP[(138.20±9.30)mmHg vs.(165.80±12.30)mm Hg],DBP[(84.20±6.05)mm Hg vs.(98.80±7.60)mm Hg]levels were lower than those in the control group,P<0.05.The total effective rate of the observation group patients was 97.61%,which was significantly higher than 80.95%of the control group,P<0.05.In terms of quality of life,the physical function scores of the observation group were[(88.80±5.50)points vs.(80.50±3.50)points],psychological function scores[(92.05±4.50)points vs.(82.50±4.30)points],social function score[(90.20±4.50)points vs.(80.80±4.30)points,material life score[(89.80±6.50)points vs.(80.50±4.50)points]were significantly higher than the control group,P<0.05.Conclusion Compared with simple hemodialysis treatment,hemodialysis-perfusion tandem treatment of uremic hemodialysis refractory hypertension has a significant effect on lowering blood pressure,thereby improving the prognosis of patients and improving the quality of life of

关 键 词：尿毒症 血液透析 顽固性高血压 血液透析-灌流串联 血压 生活质量 

分 类 号：R544.1[医药卫生—心血管疾病]