冰冻血浆与悬浮红细胞等比例输注在创伤后失血性休克患者中的应用效果  

Effect of Equal Ratio Transfusion of Frozen Plasma to Suspended Red Blood Cells in Patients with Hemorrhagic Shock after Trauma

作　　者：陈淑芬[1] CHEN Shufen(Xiamen Hospital of Traditional Chinese Medicine,Xiamen 361000,China)

机构地区：[1]厦门市中医院,福建厦门361000

出　　处：《中国医药指南》2022年第26期89-91,共3页Guide of China Medicine

摘　　要：目的探究冰冻血浆(FFP)与悬浮红细胞(SRBC)等比例输注在创伤后失血性休克患者的应用效果。方法回顾性收集2019年3月至2021年4月我院105例创伤后失血性休克患者的临床资料,根据FFP与SRBC比例不同分3组,各35例。其中观察组采用FFP:SRBC=1:1,对照1组采用FFP:SRBC=1:2,对照2组采用FFP:SRBC=1:3。比较3组病死率、入住ICU时间、住院时间、液制品(FFP、SRBC、血小板)使用情况,输注前、输注后6 h凝血功能指标[凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)]。结果观察组病死率2.86%,高于对照1组、2组的5.71%、5.71%,但3组病死率比较差异无统计学意义(P>0.05);观察组入住ICU时间、住院时间短于对照1组、对照2组(P<0.05);观察组FFP使用较对照1组、对照2组多,对照1组FFP使用较对照2组多(P<0.05),3组SRBC、血小板使用比较差异无统计学意义(P>0.05);输注后6 h观察组PT、TT、APTT较对照1组、对照2组短,FIB较对照1组、对照2组高,对照1组PT、TT、APTT较对照2组短,FIB较对照2组高(P<0.05)。结论FFP与SRBC等比例输注应用于创伤后失血性休克患者中可改善其凝血功能,缩短患者入住ICU时间和住院时间,促进病情转归。Objective To explore the effect of equal proportion infusion of fresh frozen plasma(FFP)and suspended red blood cells(SRBC)in patients with post-traumatic hemorrhagic shock.Methods From March 2019 to April 2021,the clinical data of 105 patients with post-traumatic hemorrhagic shock in our hospital were collected retrospectively.They were divided into three groups according to the ratio of FFP to SRBC,with 35 cases in each group.FFP:SRBC=1:1 was used in the observation group,FFP:SRBC=1:2 was used in the control group 1,and FFP:SRBC=1:3 was used in the control group 2.The mortality,ICU admission time,hospitalization time,use of liquid products(FFP,SRBC,platelet),coagulation function indexes[thrombin time(TT),prothrombin time(PT),activated partial thromboplastin time(APTT),fibrinogen(FIB)]before and 6 hours after infusion were compared among the three groups.Results The mortality of the observation group was 2.86%,higher than 5.71%,5.71%of the control group 1 and 2,but there was no significant difference among the three groups(P>0.05).The ICU admission time and hospitalization time of the observation group were shorter than those of the control group 1 and control group 2(P<0.05).The FFP use in the observation group was more than that in the control group 1 and the control group 2,and the FFP use in the control group 1 was more than that in the control group 2(P<0.05).There was no significant difference in the use of SRBC and platelet in the three groups(P>0.05).Six hours after infusion,PT,TT and APTT in the observation group were shorter than those in control group 1 and control group 2,FIB was higher than those in control group 1 and control group 2,PT,TT and APTT in control group 1 were shorter than those in control group 2,and FIB was higher than those in control group 2(P<0.05).Conclusion FFP and SRBC infusion in equal proportion can improve coagulation function,shorten the time of admission to ICU and hospitalization,and promote the prognosis of patients with post-traumatic hemorrhagic shock.

关 键 词：创伤后失血性休克 冰冻血浆 等比例输注 悬浮红细胞 凝血功能 

分 类 号：R441.9[医药卫生—诊断学]