超声引导下射频消融与无水乙醇消融治疗甲状腺囊实性结节的Meta分析  

Ultrasound-guided radiofrequency ablation versus percutaneous ethanol injection for the treatment of cystic-solid thyroid nodules: a meta-analysis

作　　者：周凡 穆正青 赵倩 陆军 徐长松[1] ZHOU Fan;MU Zhengqing;ZHAO Qian;LU Jun;XU Changsong(Department of Medical Ultrasound,Afiliated Huai'an No.1 People's Hospital of Nanjing Medical University,Huai'an,JiangsuProvince223300,China)

机构地区：[1]南京医科大学附属淮安第一医院超声科,223300 [2]淮安市中医院内分泌科

出　　处：《介入放射学杂志》2022年第7期679-685,共7页Journal of Interventional Radiology

基　　金：江苏省淮安市卫生健康科研面上项目(HAWJ201906)。

摘　　要：目的 对比超声引导下射频消融(RFA)与无水乙醇消融(PEI)治疗甲状腺囊实性结节的临床疗效及安全性。方法 计算机和人工检索PubMed、Cochrane、万方数据及CNKI等数据库收录的RFA与PEI治疗甲状腺囊实性结节临床疗效及安全性的临床对照研究。研究者从中提取相关资料,根据Cochrane手册标准对纳入文献的质量予以评价。结果 最终10篇文献纳入研究,患者为900例。结果显示,RFA治疗甲状腺囊实性结节的体积缩小率高于PEI,差异有统计学意义(P<0.05);两组在并发症发生率方面差异无统计学意义(P>0.05)。结论 RFA治疗甲状腺囊实性结节临床疗效优于PEI,两组的并发症发生率无明显差异。Objective To compare the clinical efficacy and safety of ultrasound-guided radiofrequency ablation(RFA) with those of percutaneous ethanol injection(PEI) in the treatment of cystic-solid thyroid nodules.Methods A computerized retrieval assisted by manual retrieval of academic papers concerning the clinical efficacy and safety comparison study of RFA versus PEI in treating cystic-solid thyroid nodules from the databases of PubMed, Cochrane Library, Wanfang data knowledge service platform and CNKI was conducted,from which the researchers extracted the relevant data. According to the Cochrane manual standard, the quality of the enrolled articles was evaluated. Results A total of ten articles including 900 patients were included in this meta-analysis. Meta-analysis showed that in treating cystic-solid thyroid nodules the volume reduction rate of RFA was higher than that of PEI, the difference between the two methods was statistically significant(P<0.05),while no statistically significant difference in the incidence of complications existed between the two methods(P>0.05). Conclusion In treating cystic-solid thyroid nodules, RFA is superior to PEI in clinical curative effect. There are no significant differences in the incidences of complications between the two methods.(J Intervent Radiol, 2022, 31: 679-685)

关 键 词：甲状腺结节 射频消融 无水乙醇消融 荟萃分析 

分 类 号：R581[医药卫生—内分泌]