鸡血藤化学成分及药理活性研究进展  被引量:60

Research Progress of Chemical Constituents and Pharmacological Activities of Jixueteng(Spatholob Caulis)

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作  者:高志杰 朱彤彤 牛新茹 刘二伟[1] 付志飞 GAO Zhijie;ZHU Tongtong;NIU Xinru;LIU Erwei;FU Zhifei(Chinese Medicine Research Institute,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)

机构地区:[1]天津中医药大学中医药研究院,天津301617

出  处:《辽宁中医药大学学报》2022年第4期67-74,共8页Journal of Liaoning University of Traditional Chinese Medicine

基  金:国家自然科学基金青年项目(81904058);“重大新药创制”科技重大专项(2019ZX09201005-002-007)。

摘  要:中药鸡血藤是豆科植物密花豆(Spatholobus suberectus Dunn)的干燥藤茎,主要分布于广东、广西及云南等地,具有活血补血、调经止痛、舒筋活络的功效,用于月经不调、血虚萎黄、麻木瘫痪、风湿痹痛等症。目前已从鸡血藤中分离出黄酮、酚酸、甾醇、萜类、木脂素、蒽醌等化学成分,具有保护心脑血管系统、抗氧化、抗肿瘤、抗病毒、肝保护、抗炎等作用。该文对近几十年来国内外有关鸡血藤化学成分和药理作用的研究进行了综述,为鸡血藤药用资源的进一步开发利用提供参考。Jixueteng(Spatholob Caulis)is the dried vine stem of Spatholobus suberectus Dunn,which is mainly distributed in Guangdong,Guangxi and Yunnan.It has the effects of promoting blood circulation and tonifying blood,regulating menstruation and relieving pain,relaxing tendons and activating collaterals,and is used for irregular menstruation,blood deficiency and yellowing,numbness and paralysis,rheumatism and arthralgia.At present,flavonoids,phenolic acids,sterols,terpenoids,lignans,an-thraquinones and other chemical components have been isolated from Jixueteng(Spatholob Caulis).In this paper,the chemical constituents and pharmacological effects of Jixueteng(Spatholob Caulis)in recent decades were reviewed to provide reference for the further development and utilization in China and abroad.

关 键 词:鸡血藤 化学成分 药理作用 

分 类 号:R282.71[医药卫生—中药学]

 

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