76例成人EB病毒感染的临床特征分析  

Analysis of the clinical characteristics of 76 cases of adult Epstein-Barr virus infection

作　　者：沈雁红 韩君华 崔明[2] 路春 唐宝玉 SHEN Yanhong;HAN Junhua;CUI Ming;LU Chun;TANG Baoyu(Medical Department,Yinhang Community Health Service Center of Yangpu District,Shanghai 200438,China;Director’s Office,Yinhang Community Health Service Center of Yangpu District,Shanghai 200438,China;Department of Ophthalmology and Otorhinolaryngology,Yinhang Community Health Service Center of Yangpu District,Shanghai 200438,China;General Practice Department of Yinhang Community Health Service Center of Yangpu District,Shanghai 200438,China)

机构地区：[1]上海市杨浦区殷行社区卫生服务中心医务科,上海200438 [2]上海市杨浦区殷行社区卫生服务中心院长办公室,上海200438 [3]上海市杨浦区殷行社区卫生服务中心眼耳鼻喉科,上海200438 [4]上海市杨浦区殷行社区卫生服务中心全科,上海200438

出　　处：《上海医药》2022年第18期28-30,共3页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的:分析成人Epstein-Barr(EB)病毒感染患者的临床特征,探讨成人EB病毒感染的临床特点。方法:选取2019年1月4日—2022年7月4日上海市杨浦区殷行社区卫生服务中心收治的76例EB病毒感染成人患者为研究对象。根据患者预后情况分为预后良好组(58例)和预后不良组(18例),对两组患者临床资料及实验室检查等相关信息进行汇总分析。结果:在预后良好组患者中,主要症状为咽痛、扁桃体肿大,分别占86.2%(50/58)和55.2(32/58),比例高于预后不良组(P <0.05)。而预后不良组患者症状主要为脾大、黄疸、淋巴结肿大和肝大等,占比分别为55.6%(10/18)、38.9%(7/18)、33.3%(6/18)和27.8%(5/18),其中脾大、黄疸和肝大占比高于预后良好组(P <0.05)。预后良好组红细胞(red blood cell,RBC)、血红蛋白(hemoglobin,HGB)及血小板计数(blood platelet,PLT)水平均高于预后不良组(P <0.05)。结论:成人EB病毒感染的临床症状表现不尽相同,症状主要为咽痛、扁桃体肿大的患者整体预后相对较好,RBC、HGB、PLT水平明显降低的患者则预后不理想。Objective:To analyze the clinical characteristics of adult Epstein-Barr(EB) virus infected patients,and explore the clinical characteristics of EB virus infection in adults.Methods:Seventy-six adult patients with EB virus infection admitted to Yinxing Community Health Service Center in Yangpu District,Shanghai from January 4,2019 to July 4,2022 were selected as the research objects.According to the prognosis of the patients,they were divided into a good prognosis group with 58 cases and a poor prognosis group with 18 cases.And the clinical data and laboratory examination of the patients in the two groups were summarized and analyzed.Results:In the patients of the good prognosis group,the main symptoms were sore throat and tonsillar enlargement,accounting for 86.2%(50/58) and 55.2%(32/58),respectively,which were higher than those in the patients of the poor prognosis group(P<0.05).But the symptoms of patients in the poor prognosis group were mainly splenomegaly,jaundice,lymphadenopathy and hepatomegaly,etc,accounting for 55.6%(10/18),38.9%(7/18),33.3%(6/18) and 27.8%(5/18),respectively,and the proportions of splenomegaly,jaundice and hepatomegaly in the poor prognosis group were higher than those in the good prognosis group(P<0.05).The levels of red blood cell(RBC),hemoglobin(HGB) and platelet count(PLT) in the good prognosis group were higher than those in the poor prognosis group and the difference was statistically significant(P<0.05).Conclusion:The manifestations of the clinical symptoms of adults EB virus infection are different,the overall prognosis of patients whose main symptoms are sore throat and tonsillar enlargement is relatively good,while the prognosis of patients whose RBC,HGB and PLT levels are significantly reduced is not ideal.

关 键 词：EB病毒 感染 成人 临床特征 

分 类 号：R373[医药卫生—病原生物学]