Microemulsion Synthesis of Mesoporous β-tricalcium Phosphate Powder with a Novel System  

作　　者：BIELEC Monikaq HUANG An XIA Yuhao DAI Honglian BIELEC Monikaq;黄岸;XIA Yuhao;戴红莲(State Key Laboratory of Advanced Technology for Materials Synthesis and Processing,Wuhan University of Technology,Shenzhen 5180oo,China;Shenzhen Institute of Wuhan University of Technology,Wuhan 430070,China)

机构地区：[1]State Key Laboratory of Advanced Technology for Materials Synthesis and Processing,Wuhan University of Technology,Shenzhen 5180oo,China [2]Shenzhen Institute of Wuhan University of Technology,Wuhan 430070,China

出　　处：《Journal of Wuhan University of Technology(Materials Science)》2022年第4期773-778,共6页武汉理工大学学报（材料科学英文版）

基　　金：Funded by the National Natural Science Foundation of China(51772233);the Key Basic Research Program of Shenzhen(No.JCYJ20200109150218836)。

摘　　要：The synthesis of mesoporous β-tricalcium phosphate(β-TCP)powder was performed by using the microemulsion approach,with hexadecyltrimethyl ammonium bromide(CTAB)/cyclohexane/n-octyl alcohol microemulsion system.The influences of different pH values and calcination temperatures on the phase composition of the β-TCP powder were studied.The in vitro proliferation of bone marrow mesenchymal stem cells(BMSCs)in the suspensions of β-TCP powders with meso-structure was studied.The phase composition,mesoporous structure,powder morphology,cell morphology and the optical density(OD)were characterized through X-ray diffraction(XRD),field emission scanning electron microscopy(FESEM),Fourier transform infrared(FTIR)spectroscopy,Nadsorption-desorption isotherms,inverted phase contrast microscopy and Multiskan spectrum,respectively.The mesoporous β-TCP powder with specific surface area of 12.85 m^(2)/g and the average pore size 7.11 nm was obtained through the microemulsion approach(100 g/L CTAB/250 mL/L cyclohexane/250 mL/L n-octyl alcohol)with a controlled pH of 7.0,after calcinating the powder at 800℃.It was confirmed that mesoporous β-TCP powder benefits the activity of BMSCs more than the non-mesoporous β-TCP powder.

关 键 词：β-tricalcium phosphate MESOPOROUS MICROEMULSION bone marrow mesenchymal stem cells 

分 类 号：TB383.3[一般工业技术—材料科学与工程]