肠外致病性大肠杆菌研究  

Research on extraintestinal pathogenic Escherichia coli

作　　者：吴桐忠[1] 张倩 张星星[1] 钟发刚[1] 何延华[1] 韩猛立[1] 黄新[1] WU Tong-zhong;ZHANG Qian;ZHANG Xing-xing;ZHONG Fa-gang;HE Yan-hua;HAN Meng-li;HUANG Xin(State Key Laboratory for Sheep Genetic Improvement and Healthy Production,Xinjiang Academy of Agricultural and Reclamation Science,Shihezi 832000,Xinjiang,China)

机构地区：[1]新疆农垦科学院省部共建绵羊遗传改良与健康养殖国家重点实验室,新疆石河子832000

出　　处：《湖北农业科学》2022年第16期147-150,168,共5页Hubei Agricultural Sciences

基　　金：新疆兵团区域创新引导计划项目(2018BB036);省部共建绵羊遗传改良与健康养殖国家重点实验室优秀中青年人才培养引导计划项目(SKLSGIHP2016A02;SKLSGIHP2017A03);新疆兵团重大科技计划项目(2017AA006);新疆兵团重点领域科技攻关计划项目(2019AB029);新疆兵团国际科技合作计划项目(2019BC004)。

摘　　要：肠外致病性大肠杆菌(Extraintestinal pathogenic E.coli,ExPEC)是近年来出现的引起人和动物免疫系统受损的主要临床病原体,由不同血清型且不发生交叉反应的菌株引起,部分菌株具有高度耐药性是导致感染严重程度的主要因素之一。对目前ExPEC的主要感染类型、毒力因子以及抵御感染的潜在手段进行了概述。Extraintestinal pathogenic E.coli(ExPEC)was the main clinical pathogen that had appeared in recent years to cause dam⁃age to the immune system of humans and animals.It consisted of a large number of different serotypes that did not cross-react.The seri⁃ousness of the infection was due to the fact that most of the infecting bacteria were highly antibiotic resistant.The main types of infec⁃tion involved in ExPEC,virulence factors,and potential means to combat the infections were discussed.

关 键 词：肠外致病性大肠杆菌 毒力因子 免疫反应 

分 类 号：S852.6[农业科学—基础兽医学]