右美托咪定滴鼻联合七氟烷吸入在小儿下腹部手术中的应用  

Application of Dexmedetomidine Nasal Drops Combined With Sevoflurane Inhalation in Children's Lower Abdominal Surgery

作　　者：曾德锋 叶笋 魏向杰 Zeng Defeng;Ye Su;Wei Xiangjie(Department of Surgical Anesthesia,Longchuan County People's Hospital,Heyuan 517300,China)

机构地区：[1]河源市龙川县人民医院手术麻醉科,广东河源517300

出　　处：《哈尔滨医药》2022年第4期9-11,共3页Harbin Medical Journal

摘　　要：目的探讨小儿下腹部手术中应用右美托咪定滴鼻联合七氟烷吸入麻醉诱导的临床效果。方法选取进行腹部手术的88例患儿作为研究对象,按麻醉方式分为观察组和对照组各44例,观察组予以右美托咪定滴鼻联合七氟烷吸入,对照组予以七氟烷吸入,比较两组患儿麻醉恢复期各指标、血流动力学指标、镇静满意度、术后躁动评分以及麻醉恢复期的不良反应。结果观察组患儿恢复时停留时间、睁眼时间、拔管时间均优于对照组(P<0.05),切皮后2h后,观察组平均动脉压、心率指标优于对照组(P<0.05),观察组患儿镇静满意度显著高于对照组(P<0.05),观察组患儿苏醒5min、15min后术后躁动评分均低于对照组(P<0.05)。结论右美托咪定滴鼻联合七氟烷吸入应用于小儿下腹部手术效果明确,有助于稳定血流动力学,有效改善患儿术后躁动,且安全性高。Objective To explore the clinical effect of dexmedetomidine nasal drops combined with sevoflurane inhalation anesthesia induction in children's lower abdominal surgery.Methods 88 children who underwent abdominal were selected as the research objects,according to the anesthesia method,they were divided into observation group and control group,each with 44 cases,The observation group was given dexmedetomidine nasal drip combined with sevoflurane inhalation,and the control group was given sevoflurane inhalation.The indexes,hemodynamic indexes,satisfaction degree of sedation,The indexes,hemodynamic indexes,satisfaction degree of sedation,postoperative restlessness score and adverse reactions during the recovery period of anesthesia were compared between the two groups of children.Results The staying time,eye-opening time,and extubation time of the observation group were better than those of the control group(P<0.05).Two hours after skin incision,the observation group’s average arterial pressure and heart rate index were better than those of the control group(P<0.05)The sedation satisfaction degree of the observation group was significantly higher than that of the control group(P<0.05),and the postoperative restlessness scores of the observation group were lower than those of the control group after 5 minutes and 15 minutes after waking up(P<0.05).Conclusion Dexmedetomidine nasal drops combined with sevoflurane inhalation applied to children's lower abdominal surgery has a clear effect,helps stabilize hemodynamics,effectively improves children's postoperative restlessness,and has high safety.

关 键 词：右美托咪定 经鼻给药 七氟烷 下腹部手术 

分 类 号：R726.1[医药卫生—儿科]