氯苯类化合物空气采样管的研发及其配套测定方法研究  

Research and development of an air sampling tube for chlorobenzene compounds and its supporting determination method

作　　者：凌伟洁[1] 戎伟丰[2] 吴诗华 郭冠浩[1] 陈纠[1] 刘移民[1] Ling Weijie;Rong Weifeng;Wu Shihua;Guo Guanhao;Chen Jiu;Liu Yimin(Guangzhou Twelfth People's Hospital(Guangzhou Occupational Disease Prevention and Treatment Hospital)Occupational Health Assessment and Monitoring Center,Guangzhou 510620,China;Guangdong Province Hospital for Occupational Disease Prevention and Treatment Poison Control Station,Guangzhou 510300,China)

机构地区：[1]广州市第十二人民医院(广州市职业病防治院)职业卫生评价检测中心,广州510620 [2]广东省职业病防治院毒化监测所,广州51030

出　　处：《中华劳动卫生职业病杂志》2022年第8期613-619,共7页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：广东省自然科学基金(2020A1515010893);广州市高水平临床重点专科建设项目职业病科(穗卫函[2019]1555号);广州市医学重点学科建设项目(2021-2023年)。

摘　　要：目的研发一种GDH-3空气采样管用于同时采集空气中12种氯苯类化合物(CBs),并建立与其配套的测定方法。方法于2020年10月,采用GDH-3空气采样管采集空气中以蒸气态和气溶胶态共存的12种CBs,用3.00 ml甲苯洗脱15 min后,以DB-23毛细管色谱柱分离,微池电子捕获检测器测定。结果本方法测定12种CBs的定量测定范围为0.71×10^(-3)~2000.00 mg/L,相关系数为0.99967~0.99998;最低检出质量浓度为0.04~112.63μg/m^(3),最低定量质量浓度为0.14~375.42μg/m^(3)(样品溶液体积为3.00 ml,采样体积为15.00 L);平均洗脱效率为96.00%~104.00%;批内精密度为2.54%~6.12%,批间精密度为3.85%~7.87%;样品在室温下可密封保存15 d以上。结论研发的GDH-3空气采样管可用于同时采集空气中12种CBs,建立的配套测定方法符合职业卫生标准检测方法的测定要求,适用于空气中12种CBs的同时测定。Objective To establish a GDH-3 air sample tube for simultaneous determination of twelve kinds of chlorobenzene compounds(CBs)in workplace air by gas chromatography.And to established a matching determination method.Methods In October 2020,the vapor and aerosol CBs in workplace air were collected by GDH-3 air sampling tube,and desorption and elution with 3.00 ml toluene for 15 min,then the solution separated by DB-23 capillary column,and finally detected with microcell electron capture detector.Results The quantitative determination ranges of twelve isomers of CBs were 0.71×10^(-3)-2000.00 mg/L,with the correlative coefficients were 0.99967-0.99998.The minimum detectable concentrations were 0.04-112.63μg/m^(3),and the minimum quantification concentrations were 0.14-375.42μg/m^(3)(15.00 L sample,3.00 ml sample solution).The average elution efficiencies were 96.00%-104.00%.The within-run relative standard deviations(RSDs)were 2.54%-6.12%,and the between-run RSDs were 3.85%-7.87%.Sealed samples could be stable at room temperature for at least 15 days.Conclusion GDH-3 air sample tube can be used for simultaneous determination of twelve kinds of CBs in workplace air by gas chromatography.The established supporting measurement method meets the measurement requirements of the occupational health standard detection method,and the it's suitable for the simultaneous determination of 12 kinds of CBS in the air.

关 键 词：空气采样管 氯苯类化合物 空气 

分 类 号：R134.4[医药卫生—劳动卫生]