前交通动脉瘤栓塞术后复发的危险因素分析  

Risk factors for the recurrence of anterior communicating aneurysm after embolization therapy

作　　者：陈杰飞[1] 周志宇[1] 谢昌纪[1] 韦成聪[1] CHEN Jiefei;ZHOU Zhiyu;XIE Changji;WEI Chengcong(Department of Neurosurgery,National Hospital of Guangxi Zhuang Autonomous Region,Nanning 530001,Guangxi,China)

机构地区：[1]广西壮族自治区民族医院神经外科,广西南宁530001

出　　处：《右江医学》2022年第9期692-696,共5页Chinese Youjiang Medical Journal

摘　　要：目的 分析前交通动脉瘤患者接受栓塞术后复发的危险因素。方法 纳入2011年7月—2021年11月广西壮族自治区民族医院收治的73例前交通动脉瘤患者作为研究对象,所有患者接受血管内栓塞介入治疗,术后随访跟踪,记录患者复发情况,整理患者临床资料进行回顾性分析。结果 随访期间,6例患者复发,其中2例出现二次破裂出血,复发率为8.22%。前交通动脉瘤术后复发的单因素比较分析显示,年龄≥60岁、Hunt-Hess分级≥3级、Fisher分级≥Ⅱ级、mRS评分持平或增高、直接栓塞、部分栓塞与前交通动脉瘤栓塞术后复发有关(P<0.05)。经二分类非条件logistic回归分析,结果显示:年龄≥60岁、Hunt-Hess分级≥3级、Fisher分级≥Ⅱ级、直接栓塞治疗、部分栓塞等是影响前交通动脉瘤栓塞术后复发的独立危险因素(P<0.05)。结论 影响前交通动脉瘤栓塞术后复发的危险因素众多,主要与患者年龄、Hunt-Hess分级、Fisher分级、栓塞治疗方式、栓塞程度等存在关联性,临床需要予以高度重视。Objective To analyze the risk factors for the recurrence of anterior communicating aneurysm after embolization therapy. Methods 73 patients with anterior communicating aneurysms treated in the National Hospital of Guangxi Zhuang Autonomous Region from July 2011 to November 2021 were selected as the objects of study. All patients received endovascular embolization interventional therapy, and were followed up after operation;and the recurrences were recorded, and the clinical data of patients were sorted out and analyzed retrospectively. Results During the follow-up, 6 patients were found to experience recurrence, including 2 of them with secondary rupture bleeding, and the rate of recurrence was 8.22%. The univariate comparative analysis of postoperative recurrence of anterior communicating aneurysm showed that age≥60 years, Hunt-Hess grade≥3, Fisher grade≥Ⅱ, mRS score equal or higher, direct embolization, partial embolization were associated with postoperative recurrence of anterior communicating aneurysm(P<0.05). The binary unconditional logistic regression analysis showed that age≥60 years, Hunt-Hess grade≥3, Fisher grade≥Ⅱ, direct embolization and partial embolization were independent risk factors for postoperative recurrence of anterior communicating aneurysm(P<0.05). Conclusion There are many risk factors affecting the recurrence of anterior communicating aneurysms after embolization therapy, which are mainly related to the patient’s age, Hunt-Hess grade, Fisher grade, embolization treatment, and embolization degree, etc. to which great attention needs to be paid in clinical practice.

关 键 词：前交通动脉瘤 复发 栓塞术 危险因素 

分 类 号：R651.12[医药卫生—外科学]