1例头孢哌酮-舒巴坦钠致凝血功能异常患者的治疗过程及其药学监护  

Treatment Process and Pharmaceutical Care of One Patient with Abnormal Coagulation Function Caused by Cefoperazone-Sulbactam Sodium

作　　者：郭江萍 李延超 GUO Jiang-ping;LI Yan-chao(People's Hospital of Kizilsu Kirghiz Autonomous Prefecture,Atux Xinjiang 845350,China)

机构地区：[1]克孜勒苏柯尔克孜自治州人民医院,新疆阿图什845350

出　　处：《抗感染药学》2022年第5期738-741,共4页Anti-infection Pharmacy

摘　　要：目的:分析头孢哌酮-舒巴坦钠致患者凝血功能异常的治疗过程和药学监护,为头孢哌酮-舒巴坦钠的用药安全和不良反应处置提供参考。方法:患者在临床治疗过程中出现不明原因的凝血功能异常,临床药师通过分析患者的用药史,结合相关药物的药学特性,协助医生制定针对性处理方案,并实施药学监护。结果:通过排查患者用药情况,结合相关文献资料,基本判定患者的凝血功能异常是由头孢哌酮-舒巴坦钠所致,随即停用该药,并进行对症处理,最终患者凝血功能很快恢复正常。结论:凝血功能异常是头孢哌酮-舒巴坦钠较为常见的不良反应,临床药师在开展药学查房时应主动关注相关患者用药后的凝血功能,以协助医生在药物不良反应出现时进行相应处置,确保患者用药安全性。Objective:To analyze the treatment process and pharmaceutical care of the patient with abnormal coagulation function caused by cefoperazone-sulbactam sodium,and provide reference for the medication safety and adverse reaction response of cefoperazone-sulbactam sodium.Methods:The patient developed unexplained abnormal coagulation function during clinical treatment.Clinical pharmacists assisted doctors in developing targeted treatment regimens and implemented pharmaceutical care by analyzing the patient’s medication history and combining the pharmaceutical characteristics of related drugs.Results:By investigating the drug use of the patient and combining with relevant literature,it was basically determined that the abnormal coagulation function of the patient was caused by cefoperazone-sulbactam sodium;then the drug was discontinued immediately and symptomatic treatment was carried out.Finally,the coagulation function of the patient recovered quickly.Conclusion:Abnormal coagulation function is a common adverse reaction of cefoperazone-sulbactam sodium.Clinical pharmacists should actively pay attention to the coagulation function of related patients after medication during the pharmaceutical ward rounds,so as to assist doctors in responding to adverse drug reactions and ensure the medication safety of patients.

关 键 词：头孢哌酮-舒巴坦钠 凝血功能异常 药物不良反应 药学监护 

分 类 号：R97[医药卫生—药品]