经典名方升阳益胃汤的历史沿革与现代临床应用研究概况  

Historical Evolution and Modern Clinical Application of Shengyang Yiweitang

作　　者：王小文 白建英 芦迪 范瑞菊 张秀芬 杨贵真 徐昭娟 李付平 康立英 WANG Xiaowen;BAI Jianying;LU Di;FAN Ruiju;ZHANG Xiufen;YANG Guizhen;XU Zhaojuan;LI Fuping;KANG Liying(Graduate School,School of Nursing,Hebei University of Chinese Medicine,Shijiazhuang 050200,China)

机构地区：[1]河北中医学院研究生学院,护理学院,石家庄050200

出　　处：《中国实验方剂学杂志》2022年第19期173-184,共12页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：河北省中医药管理局科研计划项目(Z2022007);河北省中医药康养照护研究重点实验室项目(SZX2021025);河北省自然科学基金项目(H2015423040)。

摘　　要：升阳益胃汤是国家中医药管理局首批公布的百首经典名方之一,最早来源于金代医家李东垣的《内外伤辨惑论》中,是由黄芪、人参、甘草、白术、茯苓、半夏、陈皮、独活、防风、羌活、柴胡、白芍、泽泻及黄连14味药物组成,功效益气升阳、清热除湿,主治脾胃虚弱,湿热滞留证。笔者采用文献计量学的方法,从升阳益胃汤的处方来源、组成用量、制法用法、功效主治、组方原理、药物基原与炮制及现代临床应用方面进行系统梳理,探明了其历史沿革,确定了其关键信息。同时,发现升阳益胃汤现代临床应用极广,适用于多系统病证,其中消化系统(264次)最多,占41.71%;其次为泌尿生殖系统(57次)占9.00%,神经系统(48次)占7.58%。治疗范围虽广,但中医学病机总属“脾胃虚弱”,充分体现了李东垣“内伤脾胃,百病由生”的脾胃内伤学说学术思想。通过对记载升阳益胃汤的古籍及现代文献综述,确定其关键信息内容,以期为升阳益胃汤合理临床应用、后续深入研究及开发提供更准确的参考。Shengyang Yiweitang is one of the first 100 classical prescriptions published by the National Administration of Traditional Chinese Medicine.It originated from the Clarifying Doubts about Damage from Internal and External Causes by physician LI Dongyuan of Jin dynasty,and is composed of Astragali Radix,Ginseng Radix et Rhizoma,Glycyrrhizae Radix et Rhizoma,Atractylodis Macrocephalae Rhizoma,Poria,Pinelliae Rhizoma,Citri Reticulatae Pericarpium,Angelicae Pubescentis Radix,Saposhnikoviae Radix,Notopterygii Rhizoma et Radix,Bupleuri Radix,Paeoniae Radix Alba,Alismatis Rhizoma,and Coptidis Rhizoma.With the effects of replenishing Qi,promoting Yang,clearing heat and removing dampness,Shengyang Yiweitang is used to treat spleen-stomach weakness and dampness-heat accumulation syndrome.Using bibliometrics,the authors systematically sorted out the source,composition,dosage,preparation,efficacy,indications,principle of composition,origin and processing of drugs,and modern clinical application of the prescription,and explored its history and key information.Additionally,it was found that Shengyang Yiweitang was widely used in modern clinical practice and was suitable for multisystem diseases,of which digestive system(264)was the most common,accounting for 41.71%,followed by urogenital system(57,9.00%)and nervous system(48,7.58%).Although the treatment scope was wide,the pathogenesis of the diseases in traditional Chinese medicine belongs to"spleen-stomach weakness",which fully reflected Li's academic thought of"internal injury of spleen and stomach leads to various diseases".The key information of Shengyang Yiweitang was determined by summarizing the relevant ancient books and modern literature,so as to provide accurate reference for its rational clinical application and further research and development.

关 键 词：经典名方 升阳益胃汤 历史沿革 临床应用 关键信息 文献研究 

分 类 号：R289[医药卫生—方剂学] R22[医药卫生—中药学] R2-031[医药卫生—中医学] R33