台州市男性HIV感染者HPV疫苗接种意愿及相关因素  

The willingness of HPV vaccination and related factors among HIV-positive males in Taizhou city

作　　者：张静[1] 林海江[2] 沈伟伟[2] 高眉扬[1] 丁盈盈[1] 何纳[1] 陈潇潇[2] 刘星[1] ZHANG Jing;LIN Haijiang;SHEN Weiwei;GAO Meiyang;DING Yingying;HE Na;CHEN Xiaoxiao;LIU Xing(Department of Epidemiology,School of Public Health,and the Key Laboratory of Public Health Safety of Ministry of Education,Fudan University,Shanghai 200032,China;Taizhou City Center for Disease Control and Prevention,Taizhou 318000)

机构地区：[1]复旦大学公共卫生学院流行病学教研室,公共卫生安全教育部重点实验室,上海200032 [2]台州市疾病预防控制中心,浙江台州318000

出　　处：《中国艾滋病性病》2022年第9期1064-1069,共6页Chinese Journal of Aids & STD

基　　金：国家自然科学基金青年项目(81803291);上海市卫生健康委员会青年科研课题(20164Y0232);复旦大学新进青年教师科研起步项目(JJF201041,JIF201104,IDF201021/001);台州市科技计划项目(21YWA68)。

摘　　要：目的了解台州市男性HIV感染者HPV知晓情况和HPV疫苗接种意愿,并探索相关因素。方法在台州市四区县采用横断面调查方法,于2016-2019年招募随访管理的男性HIV感染者。采用问卷调查收集研究对象社会人口学、性向与性行为、HPV知晓和HPV疫苗接种意愿等信息,同时采集肛管拭子样本进行HPV检测。采用χ^(2)检验和Logistic回归等分析HPV疫苗接种意愿的相关因素。结果共纳入711例男性HIV感染者,平均年龄(45.4±14.4)岁。其中12.5%(89人)知晓HPV;经过简要介绍后,42.3%(301人)的研究对象愿意接种HPV疫苗。未婚(56.9%)、有同性性行为(47.8%)、最近半年有同性肛交性行为者(59.3%)和知晓HPV者(70.8%)有更高的HPV疫苗接种意愿(P<0.05)。逐步回归结果显示在婚(OR=0.62,95%CI:0.41~0.94)、离异或丧偶(OR=0.35,95%CI:0.20~0.61)与HPV疫苗接种意愿负相关;双性性向(OR=2.78,95%CI:1.52~5.07)、最近半年有同性肛交性行为(OR=1.77,95%CI:1.07~2.92)以及HPV知晓(OR=3.12,95%CI:1.79~5.43)与HPV疫苗接种意愿正相关。结论台州市男性HIV感染者HPV知晓率较低,有高危性行为者HPV疫苗接种意愿更高。应加强HPV相关知识健康教育,提高知晓率,并在资源充分时考虑对HPV感染高危男性开展疫苗接种。Objective To explore the awareness of human papillomavirus(HPV)awareness,the willingness to HPV vaccination and related factors among HIV-positive males in Taizhou.Methods A cross-sectional survey was conducted in four counties in Taizhou.HIV-positive males were recruited through routine follow-up and management by Taizhou prefectural CDC from 2016 to 2019.A questionnaire interview was administered to collect data on sociodemographic,sexual orientation,sexual behavior,HPV awareness,the willingness to HPV vaccination and other characteristics.In addition,an anal swab was collected for HPV genotyping.Theχ^(2)test and logistic regression analysis were used to explore related factors of the willingness to HPV vaccination.Results A total of 711 HIV-positive males were surveyed.Average age was 45.4±14.4 years.12.5%(89)of HIV-positive males were aware of HPV.After a brief introduction,42.3%(301)were willing to receive the HPV vaccine.Those who were never married(56.9%),had homosexual behaviors(47.8%),had homosexual anal sex in the last six months and those who were aware of HPV(70.8%)had higher HPV vaccination willingness.The stepwise regression model showed that those who were currently married(OR=0.62,95%CI:0.41-0.94),widowed or divorced(OR=0.35,95%CI:0.20-0.61)was associated with a lower willingness for HPV vaccination.Bisexual orientation(OR=2.78,95%CI:1.52-5.07),had homosexual anal sex in the last six months(OR=1.77,95%CI:1.07-2.92)and aware of HPV(OR=3.12,95%CI:1.79-5.43)were associated with the higher willingness of HPV vaccination.Conclusions The HPV awareness among HIV-positive males in Taizhou is low,and males who had high-risk behaviors have a higher willingness for HPV vaccination.Health education about HPV prevention should be strengthened to improve HPV awareness.HPV vaccination in males at high risk of HPV infection should be considered when resources are available.

关 键 词：人乳头瘤病毒 疫苗接种意愿 艾滋病病毒 男性 

分 类 号：R373.9[医药卫生—病原生物学]