防己诺林碱药理作用研究进展  

Progress on Pharmacological Effect of Fangchinoline

作　　者：王斐然 张会敏[2] 林永强 张秋红 WANG Fei-ran;ZHANG Hui-min;LIN Yong-qiang;ZHANG Qiu-hong(Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Shandong Academy of Chinese Medicine,Jinan 250014 China;NMPA Key Laboratory for Quality Evaluation of Gelatin Products,Shandong Engineering Laboratory for Standard Innovation and Quality Evaluation of TCM,Shandong Engineering Research Center for Generic Technologies of Traditional Chinese Medicine Formula Granules,Shandong Provincial Institute for Food and Drug Control,Jinan 250101,China;Jinan Center for Food and Drug Control,Jinan 250102,China)

机构地区：[1]山东中医药大学,山东济南250355 [2]山东省中医药研究院,山东济南250014 [3]山东省食品药品检验研究院,国家药监局胶类产品质量评价重点实验室,山东省中药标准创新与质量评价工程实验室,中药配方颗粒共性技术山东省工程研究中心,山东济南250101 [4]济南市食品药品检验检测中心,山东济南250102

出　　处：《食品与药品》2022年第5期476-480,I0004,共6页Food and Drug

基　　金：山东省重点研发计划重大科技创新工程项目(编号:2021CXGC010511);山东省重点研发计划项目(编号:2020RKB24001);山东省人文社会科学课题(编号:2021-YYGL-44);山东省食品药品检验研究院平台课题(编号:SDIFDC-KY-1-2021023,SDIFDC-KY-1-2021026)。

摘　　要：防己诺林碱是防己中重要的生物碱类,具有抗癌、抗肿瘤、缓解骨质疏松、抗炎、抗病毒、视网膜保护、抑制瘢痕生长等作用;与其他药物联合用药具有协同作用。本文综述防己诺林碱的药理作用,为防己诺林碱的后续研究、开发和综合利用提供参考。Fangchinoline is an important alkaloid in Fangji,which has a wide range of anti-cancer,anti-tumor,relieving osteoporosis,anti-inflammatory,antiviral,retina protective,inhibition of scar growth and other effects.Fangchinoline also has synergistic effects when used in combination with other drugs.This paper mainly summarizes the pharmacological effects of Fangchinoline,in order to provide theoretical reference for the follow-up research,development and comprehensive utilization of Fangchinoline.

关 键 词：防己诺林碱 作用机制 药理作用 抗肿瘤 

分 类 号：R285[医药卫生—中药学]