Impact of clinical research on public health policy of neonatal screening for congenital heart disease in China  

作　　者：Miao Yang Youping Tian Pin Jia Xiaojing Ma Xiaoling Ge Xiaojing Hu Quming Zhao Fang Liu Bing Jia Weili Yan Qing Gu Guoying Huang 

机构地区：[1]National Management Office of Neonatal Screening Project for CHD,Children’s Hospital of Fudan University,National Children’s Medical Center,Shanghai 201102,China [2]Shanghai Key Laboratory of Birth Defects,Shanghai 201102,China.

出　　处：《Chinese Medical Journal》2022年第11期1261-1263,共3页中华医学杂志（英文版）

基　　金：National Key Research and Development Program(No. 2016YFC1000506);Innovation Unit of Chinese Academy of Medical Sciences(No. 2018RU002);Three-Year Planning for Strengthening the Construction of Public Health System in Shanghai(No. GWIV-24)

摘　　要：Congenital heart disease(CHD)is one of the most common congenital malformations,with a prevalence of approximately 1%in live births.[1,2]Among them,1/4 to 1/3 are major CHD,including critical CHD(CCHD)and serious CHD,which require surgical or catheter intervention before 1 year of age.[3]Major CHD,if left untreated,may cause serious outcomes,such as heart failure,cardiogenic shock,acidosis,and hypoxic-ischemic brain damage,and is one of the leading causes of infant death and childhood disability.[4]The missed diagnosis rate of CCHD in four nurseries ranges from 13%to 48%in developed countries,[4,5]but in China,is>71%before serious symptoms occur after birth.[6]Therefore,screening for CHD is useful for early detection,diagnosis,and treatment and helps to improve prognosis and reduces the medical,economic,and mental burden to both the family and the society.[5,7]

关 键 词：DIAGNOSIS CONGENITAL NURSE 

分 类 号：R722.1[医药卫生—儿科]