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作 者:李奕 庞博[1] 花宝金[1] 刘福栋 姜晓晨 张曦元 恩格尔 LI Yi;PANG Bo;HUA Baojin;LIU Fudong;JIANG Xiaochen;ZHANG Xiyuan;EN Geer(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing,100053;Beijing University of Chinese Medicine)
机构地区:[1]中国中医科学院广安门医院,北京市100053 [2]北京中医药大学
出 处:《中医杂志》2022年第17期1611-1615,共5页Journal of Traditional Chinese Medicine
基 金:国家中医药管理局中医药创新团队及人才支持计划项目(ZYYCXTD-C-202205);北京市自然科学基金(7222296);首都卫生发展科研专项自主创新项目(首发2022-2-4155);中国中医科学院科技创新工程项目(CI2021A01805)。
摘 要:从中医通道理论出发,对胃肠恶性肿瘤的发生进行探讨,认为三焦通道气化失司,水液、谷精、原气运行失常是其核心病机;胃肠结构通道功能的失常导致营卫不和、经络通道不畅导致气血失调为胃肠恶性肿瘤发生的重要病机;物质转化与能量代谢的失衡是通道功能异常进而导致胃肠恶性肿瘤发生的关键要素。形成以三焦通道为核心,以经络通道、局部组织器官为补充的胃肠恶性肿瘤认知框架,以期为系统优化中医肿瘤发生学理论、实现精准辨治提供理论依据。This study explored the genesis of malignant gastrointestinal tumors from the channel theory of tradi⁃tional Chinese medicine(TCM),which believes that uncontrolled qi transformation of sanjiao(三焦)channels,and abnormal transportation of water,grain,essence and source qi are the core pathogenesis.Dysfunction of gastrointesti⁃nal structural channels leads to ying-wei(营卫)disharmony,and blocked channels and collaterals cause disharmony of qi and blood,which is considered to be the important pathogenesis.The imbalance between substance transforma⁃tion and energy metabolism is a key factor to the dysfunction of channels and thereby leading to the occurrence of ma⁃lignant gastrointestinal tumors.In summary,the cognitive framework of malignant gastrointestinal tumors has been proposed,taking sanjiao channel as the core and supplemented with meridian channels and local tissues and organs,which can provide a theoretical basis for systematically optimizing the theory of TCM tumorigenesis and giving precise differentiation and treatment.
关 键 词:胃肠恶性肿瘤 胃癌 结直肠癌 肿瘤发生学 通道理论
分 类 号:R273[医药卫生—中西医结合]
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