胞外囊泡对改善子宫内膜容受性的作用与研究现状  

Effect of extracellular vesicles on improving en⁃dometrial receptivity and the research status.

作　　者：金晓莹[1] 辛廖冰[1] 张松英[1] JIN Xiao-ying;XIN Liao-bing;ZHANG Songying(Assisted Reproduction Unit,Department of Obstetrics and Gynecology,Sir Run Run Shaw Hospital,School of Medicine,Zhejiang University,Hang-zhou 310016,China)

机构地区：[1]浙江大学医学院附属邵逸夫医院妇产科&生殖中心,浙江杭州310016

出　　处：《中国实用妇科与产科杂志》2022年第9期895-899,共5页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：国家自然科学基金国际(地区)合作与交流项目(82061160494)。

摘　　要：子宫内膜容受性是影响胚胎顺利植入的关键因素,子宫内膜容受性异常将导致胚胎着床失败和胎盘发育异常。胚胎植入过程中,母体和胚胎的胞外囊泡的有序产生和精确协调确保了胚胎的顺利植入。间充质干细胞来源的胞外囊泡可改善病理状态下的子宫内膜容受性。Endometrial receptivity is the key factor affecting embryo implantation.Abnormal endometrial receptivity leads to embryo implantation failure and abnormal placental development.In the process of embryo implantation,the orderly generation and pre⁃cise coordination of extracellular vesicles between the maternal tissues and the embryo ensure the smooth embryo implantation.The extracellular vesicles derived from mesenchymal stem cells can improve the impaired endometrial receptivity.

关 键 词：胞外囊泡 子宫内膜容受性 间充质干细胞 

分 类 号：R711.7[医药卫生—妇产科学]