唾液酸的制备和生物活性研究进展  

Research progress in preparation and biological activity of sialic acid

作　　者：王梦花 林小仙 琚萌萌 阴佳璐 王东亮 王姝麒[1] WANG Menghua;LIN Xiaoxian;JU Mengmeng;YIN Jialu;WANG Dongliang;WANG Shuqi(School of Pharmaceutical Sciences,Shandong University,Jinan 250012,China;Beijing Xiaoxiandun Biotechnology Co.,Ltd.,Beijing 100020,China;Hebei Edible Bird′s Nest Fresh Stew Technology Innovation Center,Langfang 065700,China)

机构地区：[1]山东大学药学院,山东济南250012 [2]北京小仙炖生物科技有限公司,北京100020 [3]河北省燕窝鲜炖技术创新中心,河北廊坊065700

出　　处：《药学研究》2022年第9期600-604,共5页Journal of Pharmaceutical Research

基　　金：山东省重点研发计划重大科技创新工程项目(No.2021CXGC010511);山东省重点研发计划(No.2017GSF218049);山东大学青年学者未来计划(No.2018WLJH93)。

摘　　要：唾液酸是含9个碳的α-酮酸,唾液酸由于存在位置和形式不同,具有多种生物活性,如抗肿瘤、抗炎、抗病毒、促进神经的发育。该文结合了近几年国内外的研究,综述介绍了唾液酸的制备方法及生物活性研究进展,以期对其深入研究拓展思路。Sialic acid is aα-ketoacid containing 9 carbons,sialic acid has a variety of biological activities because of its different location and form,such as anti-tumor,anti-inflammation,antivirus,promoting nerve development.Combined with the research at home and abroad in recent years,the preparation methods and biological activity of sialic acid were reviewed in order to further study sialic acid.

关 键 词：唾液酸 制备 生物活性 

分 类 号：R915[医药卫生—微生物与生化药学]