儿童神经源性膀胱继发膀胱输尿管反流的临床治疗策略  

Clinical treatment strategies of vesicoureteral reflux secondary to neurogenic bladder in children

作　　者：徐哲明[1] 唐达星[1] Xu Zheming;Tang Daxing(National Clinical Research Center for Children's Health,Department of Urology,Affiliated Children's Hospital,Zhejiang University School of Medicine,Hangzhou 310052,China)

机构地区：[1]国家儿童健康与疾病临床医学研究中心,浙江大学医学院附属儿童医院泌尿外科,杭州310052

出　　处：《临床小儿外科杂志》2022年第9期881-885,共5页Journal of Clinical Pediatric Surgery

基　　金：浙江省科技厅公益研究计划(LGF19H090020)。

摘　　要：神经源性膀胱(neurogenic bladder,NB)是由调节排尿功能的中枢和(或)周围神经系统发生异常而引起的膀胱尿道功能障碍。膀胱输尿管反流(vesicoureteral reflux,VUR)是NB常见的并发症之一。由于继发于NB的VUR病因复杂,且每个致病因素随着病程的进展相互影响并转化。一直以来该疾病的治疗是临床工作的难点。本文概述了NB继发VUR的总体治疗策略,并从原发病治疗、保守治疗及手术治疗三方面介绍了NB继发VUR的具体治疗方法,讨论不同治疗方法的适应证、临床争议点以及应对策略。Neurogenic bladder(NB)is a dysfunction of bladder and urethra caused by abnormal central or/and peripheral nervous system of regulating urinary function.Vesicoureteral reflux(VUR)is one of the most common complications of NB.Since the underlying etiology of VUR secondary to NB is rather complicated and many pathogenic factors affects each other with the progress of the disease,a proper treatment of the disease has always been a clinical dilemma.This review summarized the overall treatment strategies of secondary VUR in NB and focused upon treatment of primary disease,conservative measures and surgery.Also clinical indications for different tretments,current controversies and counter-measures were discussed.

关 键 词：膀胱 神经原性 输尿管镜检查 尿道疾病 肾功能不全/病因学 

分 类 号：R726.9[医药卫生—儿科]