低能量平衡膳食联合有氧运动对单纯性肥胖儿童体脂代谢、胰岛素抵抗及氧化应激反应的影响  

Effects of Low Energy Balanced Diet Combined with Aerobic Exercise on Body Fat Metabolism,Insulin Resistance and Oxidative Stress Response in Simple Obese Children

作　　者：古丽加娜提·阿布拉克木 王敏囡 何艳红[1] 阿曼古丽·卡德尔 热娜·买买提[1] 李蓉蓉 Gulijianati·abulakemu;WANG Min-nan;HE Yan-hong;Amanguli·kader;Rena·maimaiti;LI Rong-rong(Department of Child Healthcare,The First Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang,830000,China;Department of Clinical Nutrition,The First Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang,830000,China)

机构地区：[1]新疆医科大学第一附属医院儿童保健科,新疆乌鲁木齐830000 [2]新疆医科大学第一附属医院临床营养科,新疆乌鲁木齐830000

出　　处：《现代生物医学进展》2022年第18期3459-3462,3533,共5页Progress in Modern Biomedicine

基　　金：新疆维吾尔自治区自然科学基金项目(2017D01C365)。

摘　　要：目的:观察单纯性肥胖儿童经有氧运动、低能量平衡膳食联合干预后,机体体脂代谢、胰岛素抵抗及氧化应激反应的变化。方法:选择2019年8月~2021年7月期间新疆医科大学第一附属医院接收的单纯性肥胖儿童93例,将纳入的患儿根据随机数字表法分为对照组和研究组,各为46例和47例。对照组患儿接受低能量平衡膳食干预,研究组患儿接受低能量平衡膳食联合有氧运动干预。对比两组体脂代谢、胰岛素抵抗、血脂及氧化应激反应相关指标变化情况。结果:研究组干预12周后体质量指数(BMI)、甘油三酯(TG)、体脂含量、总胆固醇(TC)、体脂率、腰臀比、空腹胰岛素(FINS)、低密度脂蛋白(LDL-C)、空腹血糖(FPG)、蛋白质羰基(PC)、C肽、胰岛素抵抗指数(HONA-IR)、丙二醛(MDA)低于对照组(P<0.05)。研究组干预12周后高密度脂蛋白(HDL-C)、超氧化物歧化酶(SOD)高于对照组(P<0.05)。结论:低能量平衡膳食联合有氧运动可促进单纯性肥胖儿童体脂代谢改善,减轻胰岛素抵抗及氧化应激反应,效果确切。Objective:To observe the changes of body fat metabolism,insulin resistance and oxidative stress response in simple obese children after aerobic exercise and low energy balanced diet.Methods:93 cases of simple obese children who were received in The First Affiliated Hospital of Xinjiang Medical University from August 2019 to July 2021 were selected.The included children were divided into control group and study group by random number table method,46 cases and 47 cases respectively.The children in the control group received low energy balanced diet intervention,the children in the study group received the intervention of low energy balanced diet combined with aerobic exercise.The changes of body fat metabolism,insulin resistance,blood lipid and oxidative stress response were compared between the two groups.Results:12 weeks after intervention,the body mass index(BMI),triglyceride(TG),body fat content,total cholesterol(TC),body fat rate,waist hip ratio,fasting insulin(FINS),low density lipoprotein(LDL-C),fasting plasma glucose(FPG),protein carbonyl(PC),C-peptide,insulin resistance index(HONA-IR),malondialdehyde(MDA)in the study group were lower than those in the control group(P<0.05).12 weeks after intervention,high density lipoprotein(HDL-C)and superoxide dismutase(SOD)in the study group were higher than those in the control group(P<0.05).Conclusion:Low energy balanced diet combined with aerobic exercise can promote the improvement of body fat metabolism in simple obese children,and reduce insulin resistance and oxidative stress,and with exact effect.

关 键 词：低能量平衡膳食 有氧运动 单纯性肥胖 体脂代谢 胰岛素抵抗 氧化应激 

分 类 号：R723.14[医药卫生—儿科]